Publications

Arja Rautio – Recent publications (since 2011)


Pacyna JM, Cousins IM, Halsall C, Rautio A, Pawlak J, Pacyna EG, Sundseth K, Wilson S, Munthe J. Impacts on human health in the Arctic owing to climate-induced changes in contaminant cycling – the EU ArcRisk project policy outcome. Environmental Science and Policy 50: 200-213, 2015. http://dx.doi.org/10.1016/j.envsci.2015.02.010.

Sundseth K, Pacyna JM, Banel A, Pacyna EG, Rautio A. Climate change impacts on environmental and human exposure to mercury in the Arctic. Int J Environ Res Public Health 12: 3579-3599; doi: 10.3390/ijerph120403579, 2015.

Pakanen L, Pääkkönen T, Ikäheimo T, Rintamäki H, Leppäluoto J, Kaija H, Kortelainen M-L, Rautio A, Porvari K. Urinary thrombomodulin and catecholamine levels are interrelated in healthy volunteers immersed in cold and warm water. Temperature. Online

Murtomaa-Hautala M, Ruokojärvi P, Viluksela M, Rautio A: Temporal trends in the levels of polychlorinated dioxins, -furans, -biphenyls and polybrominated diethyl ethers in bank voles in Northern Finland. Science of the Total Environment 526: 70-76, 2015. http://dx.doi.org/10.1016/j.scitotenv.2015.04.067.

Rautio A, Poppel B, Young K (contributing authors: Emelyanova A, Juutilainen S, Sunnari V): Human Health and Well-Being. In book: Arctic Human Development Report II - Regional Processes and Global Linkages (eds. Larsen JN and Fondahl G). Tema Nord, ISSN0908-6692; 2014:567. pp. 297-346, 2014.

Luoto T, Heikkinen HI, Rautio A. Globalizing challenges of well-being in the Finnish North. Nordia Geographical Publications 43: 1, 45-57, 2014.

Tanja Nordström, Tuula Hurtig, Alina Rodriguez, Jukka Savolainen, Arja Rautio, Irma Moilanen, Anja Taanila and Hanna Ebeling. Different Risk Factors Between Disruptive Behavior Disorders and ADHD in Northern Finland Birth Cohort 1986. The online version: DOI: 10.1177/1087054714538654.

Nieminen P, Lehtiniemi H, Vähäkangas K, Huusko A, Rautio A: Summarizing the reported findings between quantitative exposure and outcome variables from epidemiologic studies in a consistent form: The effect of exposure to polychlorinated biphenyls (PCBs) on birth weight as an example. Epidemiology Biostatistics and Public Health, 10 (No 4), e8854, 2013; DOI:10.2427/8854. http://ebph.it/article/view/8854.

Juutilainen S, Miller R, Heikkilä L, Rautio A. Structural Racism and Indigenous Health: What Indigenous Perspectives of Residential School and Boarding School Tell Us? A Case Study of Canada and Finland.  The International Indigenous Policy Journal 2014, Volume 5 / Issue 3. Article 3.

Oravisjärvi K, Pietikäinen M, Ruuskanen J, Niemi S, Lauren M, Voutilainen A, Keiski RL, Rautio A: Diesel particle composition after exhaust after-treatment of an off-road diesel engine and modeling of deposition into the human lung. Journal of Aerosol Science, 2014, 69: 32-47.

Nieminen P, Lehtiniemi H, Vähäkangas K, Huusko A, Rautio A:. Standardised regression coefficient as an effect size index in summarizing findings in epidemiological studies. Epidemiology Biostatistics and Public Health - 2013, Volume 10 (4): e8854-1 -15,  DOI:10.2427/8854.

Lépy E, Heikkinen H, Karjalainen TP, Tervo-Kankare K, Kauppila, P, Suopajärvi T, Ponnikas, J, Siikamäki P, Rautio A: Multidisciplinary and participatory approach for assessing local vulnerability of tourism to climate change. Scand J Hospitality and Tourism, 2014. http://dx.doi.org/10.1080/15022250.2014.886373.

Näyhä S, Lankila T, Rautio A, Koiranen M, Tammelin T, Taanila A, Rusanen J, Laitinen J. Body mass index and overweight in relation to residence distance and population density: experience from the Northern Finland Birth Cohort 1966. BMC Public Health. BMC Public Health.2013, 13:938. DOI: 10.1186/10.1186/1471-2458-13-938. URL: http://www.biomedcentral.com/1471-2458/13/938

Nilsson LM, Destonuni G, Berner J, Dudarev A, Mulvad G, Odland JO, Rautio A, Tikhonov C, Evengård B. A call for urgent monitoring of food and water security based on relevant indicators for the arctic. AMBIO 2013 42: 816-22. doi: 10.1007/s13280-013-0427-1. Epub 2013 Aug 6. (Perspective)

Nilsson LM, Berner J, Dudarev A, Mulvad G, Odland JO, Rautio A, Tikhonov C, Evengård B. Selecting indicators of food and water security in the Arctic health context – results from an international workshop discussion. Int J Circumpolar Health 2013 72: 21530 – http://dx.doi.org/10.3402/jch.v720.21530. (Conference and workshop report)

Abass, K, Reponen P, Mattila S, Rautio A, Pelkonen O: Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models. Toxicol Letters, 2014: 224(2):300-9. 2013 Sep 7. doi:pii: S0378-4274(13)01295-2. 10.1016/j.toxlet.2013.08.023.

Abass K, Reponen P, Mattila S, Rautio A, Pelkonen O: Comparative metabolism of benfuracarb in in vitro mammalian hepatic microsomal model and its implications for chemical risk assessment.Toxicol Letters, 2014: 224: 290-9. Aug 16. doi:pii: S0378-4274(13)01281-2. 10.1016/j.toxlet.2013.08.009.

Abass K, Huusko A, Nieminen P, Myllynen P, Pelkonen O, Vähäkangas K, Rautio A. Estimation of health risk by using toxicokinetic modeling: a case study of polychlorinated biphenyl PCB153. Hazardous Materials 261: 1-10, 2013 http://dx.doi.org/10.1016/j.hazmat.2013.07.011

Rönkä AR, Taanila A, Koiranen M, Sunnari V, Rautio A: Associations of deliberate self-harm with loneliness, self-rated health and life satisfaction in adolescence: Northern Finland Birth Cohort 1986 Study.  Int J Circumpolar Health 2013, 72: 21085 - http://dx.doi.org/10.3402/ijch.v72i0.21085

Rönkä AR, Rautio A, Koiranen M, Taanila A, Sunnari V: Experience of loneliness among adolescent girls and boys: Northern Finland Birth Cohort 1986 Study.  J Youth Studies, 17: 183-203,2014. http://dx.doi.org/10.1080/13676261.2013.805876

Emelyanova A, Rautio A: Perspectives for Population Ageing in the Russian North. J Population Aging 6:161-187, 2013. Doi: 10.1007/s12062-013-9086-z.

Lankila T, Näyhä S, Rautio A, Koiranen M, Rusanen J, Taanila A: Health and well-being of movers in rural and urban areas – a grid-based analysis of Northern Finland Birth Cohort 1966. Social Science Medicine, 76 (2013) 169-178. doi:10.1016/j.socscimed.2012.10.021.

Nieminen P, Lehtiniemi H, Huusko A, Vähäkangas K, Rautio A: Polychlorinated biphenyls (PCBs) in relation to secondary sex ratio – a systematic review of published studies. Chemosphere 91: 131-138, 2013, dx.doi.org/10.1016/j.chemosphere.2012.11.019.

Abass K, Turpeinen M, Rautio A, Hakkola J, Pelkonen O: Metabolism of pesticides by human cytochrome P450 enzymes in vitro – survey. In book: In Tech – Open Access Publisher; Insecticides/Book 3 – ISBN 979-953-307-667-5, pp 165-194, 2012.

Govats E, Nieuwenhuijsen M, Schoeters G, Ballester F, Bloemen K, de Boer M, Chevrier C, et al. (27 authors, incl Rautio A) and OBELIX/ENRIECO: Prenatal exposure to polychlorinated biphenyls (PCB) and dichlorodiphenyldichlorethylene (DDE) and birth weight: a meta-analysis within 12 European birth cohorts. Environ Health Perspect 120: 162-70, 2012.

Murtomaa M, Huitu O, Korkalainen M, Pelkonen O, Hegde N, Pohjanvirta R, Henttonen H, Rautio A, Viitala P, Viluksela M: Significant interspecies differences in induction profiles of hepatic CYP enzymes by TCDD in bank and field voles. Env Toxic Chem. 31: 663-71; on-line 2011 Dec 29. doi: 10.1002/etc. 1737. (Epub ahead of print), 2012.

Emelyanova A, Rautio A: Aging population of Barents Euro-Arctic Region. Eur Geriatric Med 3: 167-173, 2012, doi:10.1016/j.eurger.2012.03.005.

Kummu M, Wallin K, Sieppi E, Rautio A, Vähäkangas K, Myllynen P: Cadmium inhibits ABCG2 transporter function in BeWo and MCF-7/MTX cells. Placenta, 33: 859-865, 2012, doi:10.1016/j.placenta.2012.07.017.

Lankila T, Näyhä S, Rautio A, Näyhä S, Nordström T, Koiranen M, Taanila A, Rusanen J: Self-reported health in urban-rural continuum: a grid-based analysis of Northern Finland Birth Cohort 1966. Int J Public Health 57: 525-33, 2012 (published on-line 19 Aug 2011).

Callaghan TV, Johansson M, Brown RD et al (31 authors, incl Rautio A): Multiple effects of changes in Arctic snow cover. AMBIO 40: 32-45, 2011, doi:10.1007/s13280-011-0213-x

Oravisjärvi K, Pietikäinen M, Ruuskanen J, Rautio A, Voutilainen A, Keiski RL: Effects of physical activity on the deposition of traffic-related particles into the human lungs in silico. Sci Total Environ 409: 4511-8, 2011, doi:10.1016/j.scitotenv.2011.07.020.

 

Khaled M. Abass - Publications

Abass K, Koiranen M, Mazej D, Snoj J, Tratnik J, Horvat M, Hakkola J, Järvelin MR, Rautio A. Arsenic, cadmium, lead and mercury levels in blood of Finnish adults and their relation to diet, lifestyle habits and sociodemographic variables. Environmental Science and Pollution Research, (2017) 24: 1347.

Abass K.  An investigation into the formation of tebufenozide’s toxic aromatic amine metabolites in human in vitro hepatic microsomes, Pesticides Biochemistry and Physiology, 1333, (2016) pp. 73-78

Abass K, Carlsen A, Rautio A. New approaches in human health risk assessment. International Journal of Circumpolar Health, 2016, 75: 33845 - http://dx.doi.org/10.3402/ijch.v75.33845

Elsebai M, Abass K, Hakkola J, Atawia A, Farag M. The wild Egyptian artichoke as a promising functional food for the treatment of hepatitis C virus as revealed via UPLC-MS and clinical trials. Food & Function, 13(7) (2016) pp. 3006-16.

Abass K, Calsen A, Rautio A. Approches to desribe risks and future needs, In Arctic Monitoring and Assessment Programme AMAP 2015, Oslo, Norway, ISBN: 978-82-7971-093-6

Nieminen P, Abass K, Vähäkangas K, Rautio A. Statistically Non-significant Papers in Environmental Health Studies included more Outcome Variables. Biomedical and Environmental Sciences, 28 (9) (2015) pp. 666-673. DOI: 10.3967/bes2015.093

Abass K, Abd-El-Razik M, Abouelghar G. Fate and disposition of chlorpyrofos in human, In Chlorpyrifos: Technical properties, uses and effect on human health and the environment. (2015) Nova Science Publishers, New York, USA. ISBN: 978-1-63482-112-4.

Pelkonen O, Pasanen M, Tolonen A, Koskinen M, Hakkola J, Abass K, Laine J, Häkkinen M, Juvonen R, Auriola S, Storvik M, Huuskonen P, Rousu T, Rahikkala M. Reactive Metabolites in Early Drug Development: Predictive in Vitro Tools. Current Medicinal Chemistry. 2015: 22(4), 538-550.

Abass K., Reponen P, Mattila S, Rautio A, Pelkonen O. Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models. Toxicology Letters, 2014: 224(2):300-9. 2013 Sep 7.  http://dx.doi.org/10.1016/j.toxlet.2013.08.023

Abass K., From in vitro hepatic metabolic studies towards human health risk assessment: Two case studies of diuron and carbosulfan. Pesticide Biochemistry and Physiology, 107 (2013) 258–265. http://dx.doi.org/10.1016/j.pestbp.2013.08.003

Abass K., Reponen P, Mattila S, Rautio A, Pelkonen O. Comparative metabolism of benfuracarb in in vitro mammalian hepatic microsomes model and its implications for chemical risk assessment. Toxicology Letters. , 2014: 224: 290-9. Aug 16 http://dx.doi.org/10.1016/j.toxlet.2013.08.009

Abass K, Huusko A, Nieminen P, Myllynen P, Pelkonen O, Vähäkangas K, Rautio A. Estimation of health risk by using toxicokinetic modeling: a case study of polychlorinated biphenyl PCB153. Hazardous Materials 261: 1-10, 2013 http://dx.doi.org/10.1016/j.hazmat.2013.07.011

Pelkonen O., Abass K., Wiesner J. Thujone and thujone-containing herbal medicinal and botanical products: toxicological assessment. Regulatory Toxicology and Pharmacology. 2013, 65: 100–107.

Abass, K., Pelkonen, O. The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: Comparison of the N-in-one and single substrate approaches, Toxicology In vitro. 27, (2013 1584–1588).

Pelkonen O., Turpeinen, M., Hakkola J., Abass K., Pasanen M., Raunio H., How to preserve, induce or incorporate metabolism into the in vitro cellular system, Toxicology in vitro. 27, 2013 1578–1583.

Abass, K., Lämsä, V., Reponen, P., Küblbeck, J., Honkakoski, P., Mattila, S., Pelkonen, O., Hakkola, J. Characterization of human cytochrome P450 induction by pesticides, Toxicology. 2012; 294: 17-26.

Abass K, Turpeinen M, Rautio A, Hakkola J, Pelkonen O. (2012). Metabolism of pesticides by human cytochrome P450 enzymes in vitro – survey. In: Insecticides - Advances in Integrated Pest Management– Farzana Perveen (Ed.) ISBN 979-953-307-667-5, pp. 165-194., Rijeka, Croatia

Abass K., Reponen P, Mattila S. & Pelkonen O. Metabolism of α-thujone in human hepatic preparations in vitro. Xenobiotica. 2011; 14 : 101-11.

Abass K., Reponen P, Sampo M, Pelkonen O . Metabolism of Carbosulfan II. Human interindividual variability in the in vitro hepatic biotransformation and the identification of cytochrome P450 isoforms involved. Chemico-Biological Interactions, 2010; 185: 163-173.

Reponen P, Abass K., Sampo M, Pelkonen O. Overview of the metabolism and interactions of pesticides in hepatic in vitro systems. International Journal of Environmental Analytical Chemistry, 2010; 90: 429-437.

Abass K, Reponen P, Turpeinen M, Sampo M, Pelkonen O. (2010). Do cytochrome P450 enzymes contribute to the metabolism of xenobiotics in human? In: Fungicides (Carisse O., Eds), ISBN: 978-953-307-266-1, pp. 441-468. Rijeka, Croatia

Sevior D, Hokkanen J, Tolonen A, Abass K, Tursas L, Pelkonen O, Ahokas J, Rapid screening of commercially available herbal products for the inhibition of major human hepatic cytochrome P450 enzymes using the N-in-one cocktail. Xenobiotica, 2010; 40: 245-254.

Abass K., Reponen P, Sampo M, Pelkonen O. Metabolism of carbosulfan. I. Species differences in the in vitro biotransformation by mammalian hepatic microsomes including human. Chemico-Biological Interactions. 2009: 181, 210-219.

Abass K, Reponen P, Pelkonen O. (2009) Metabolic and interaction properties of selected fungicides, In Fungicides: Chemistry, Environmental, Impact and Health Effects (P. De Costa and Bezerra, Eds.), pp. 25-62. Nova Science Publishers, New York, USA.

Abass K., Turpeinen M, Pelkonen O. An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes. Journal of environmental Science and Health, Part B, 2009; 44, 553 – 563.

Abass K., Reponen P, Jalonen J, Pelkonen O. In vitro metabolism and interactions of the fungicide metalaxyl in human liver preparations. Environmental Toxicology and Pharmacology, 2007; 23: 39–47.

Abass K., Reponen P, Turpeinen M, Jalonen J, Pelkonen O. Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes. Drug Metabolism and Disposition, 2007; 35: 1634-1641.

Abass K., Reponen P, Jalonen J, Pelkonen O. In vitro metabolism and interaction of profenofos by human, mouse and rat liver preparations. Pesticides Biochemistry and Physiology, 2007; 87: 238–247.

PhD thesis (2010):

‘Metabolism and interactions of pesticides in human and animal in virto hepoatic models’ Faculty of Medicine, Institute of Biomedicine, Department of Pharmacology and Toxicology, University of Oulu, Finland. http://jultika.oulu.fi/Record/isbn978-951-42-6299-9

Last updated: 29.5.2017