Kinnunen Matti

Senior Research Fellow, D.Sc. (Tech.), Docent

HILLA Funding Services

Member of Finnish Optical Society (FOS) and European Optical Society (EOS)
Tel: +358 294 487686
Fax: +358 8 553 2774
Room: TS293
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2006: D.Sc. (Tech.), 2002: M.Sc. (Tech.), both from University of Oulu, Finland

Research experience
Non-invasive glucose monitoring, laser pulse time-of-flight technique, pulsed photoacoustic technique, optical coherence tomography; optical trapping, elastic light scattering measurements.

Areas of expertise
Optical measurements, optical tweezers, tissue optics, in vitro measurements and sample preparation, measurement of human physiological signals

Finnish, English

Selected publications

M. Kinnunen, Comparison of Optical Coherence Tomography, the Pulsed Photoacoustic Technique, and the Time-of-flight Technique in Glucose Measurements in vitro, Dissertation for D.Sc. (Tech.) degree, University of Oulu, Oulu, Finland, 2006.

Book chapter
R. Myllylä, Z. Zhao, M. Kinnunen, Pulsed Photoacoustic Techniques and Glucose Determination in Human Blood and Tissue, in Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues, CRC Press, Taylor & Francis Group, London, 419-455 (2008).

Journal papers

  1. O.  Bibikova, J. Haas, A. Lopez-Lorente, A. Popov, R. Yury, M. Kinnunen, A. Kabashin, I. Meglinski, and B. Mizaikoff, “Surface enhanced infrared absorption spectroscopy based on gold nanostars and spherical nanoparticles” Analytica Chimica Acta, accepted for publication.
  2. O. Bibikova, P. Singh, A. Popov, G. Akchurin, A. Skaptsov, I. Skovorodkin, V. Khanadeev, D. Mikhalevich, M. Kinnunen, G. Akchurin, V. Bogatyrev, N. Khlebtsov, S. Vainio, I. Meglinski, and V. Tuchin, “Shape-dependent interaction of functionalized gold nanoparticles with cultured cells at laser exposure”, Laser Physics Letters, 14 (5), 055901 (2017).
  3. S. Uusitalo, M. Kögler, A.-L. Välimaa, J. Petäjä, V. Kontturi, S. Siitonen, R. Laitinen, M. Kinnunen, T. Viitala, and J. Hiltunen, "Stability optimization of microbial surface-enhanced Raman spectroscopy detection with immunomagnetic separation beads," Opt. Eng. 56(3), 037102 (2017).
  4. O. Bibikova,   J. Haas,   A. I. López-Lorente,   A. Popov,   M. Kinnunen,  I. Meglinski and   B. Mizaikoff   “Towards enhanced optical sensor performance: SEIRA and SERS with plasmonic nanostars,” Analyst, 142(6), 951-958 (2017).
  5. M. Kinnunen, M. Ervasti, M. Jutila, S. Pantsar, A. M. Sesay, S. Pääkkönen, M. Mäki, S. Mian, H. Oinas-Kukkonen, M. Oduor, L. Kuonanoja, J. Riekki, A. Juho, P. Ahokangas, M. Perälä-Heape, H. Kotovaara, and E. Alasaarela, “Improving the Wellbeing and Safety of Children with Sensors and Mobile Technology,” Journal of Technology in Human Services, 34(4), 359–375 (2016).
  6. S. Uusitalo, M. Kögler, A.-L. Välimaa, A. Popov, Yu. Ryabchikov, V. Kontturi, S. Siitonen, J. Petäjä, T. Virtanen, R. Laitinen, M. Kinnunen, I. Meglinski, A. Kabashin, A. Bunker, T. Viitala and J. Hiltunen, “Detection of Listeria innocua on disposable SERS substrates with gold nanoparticles,” RSC Advances, 6(67), 62981-62989 (2016).
  7. K. Lee, M. Kinnunen, M. Khokhlova, E. Lyubin, A. Priezzhev, I. Meglinski, and A. Fedyanin, “Optical tweezers study of red blood cell aggregation and disaggregation in plasma and protein solutions,” Journal of Biomedical Optics, 21(3), 035001 (2016).
  8. K. Lee, M. Kinnunen, A. V. Danilina, A. V. Priezzhev, V.D. Ustinov, I. Meglinski, S. Shin"Characterization of shear stress preventing the red blood cells from aggregation at the individual cells level and in whole blood sample", Journal of Biomechanics, 49(7), 1021–1026 (2016).
  9. M. Kinnunen, S. Q. Mian, H. Oinas-Kukkonen, J. Riekki, M. Jutila, M. Ervasti, P. Ahokangas, and E. Alasaarela, “Wearable and mobile sensors connected to social media in human well-being applications,” Telematics and Informatics, 33(1), 92-101 (2016).
  10. K. Lee, A. V. Danilina, M. Kinnunen, I. Meglinski and A. V. Priezzhev, ” Probing the Red Blood Cells Aggregating Force with Optical Tweezers,” Journal of Selected Topics in Quantum Electronics 22(3), 7000106 (2016).
  11. O.  Bibikova, A. Popov, A. Bykov, A. Fales, H. Yuan, I. Skovorodkin, M. Kinnunen, S. Vainio, T. Vo-Dinh, V. Tuchin, I. Meglinski, ” Plasmon-resonant Gold Nanostars with Variable Size as Contrast Agents for Imaging Applications,” Journal of Selected Topics in Quantum Electronics, 22(3), 4600808 (2016).
  12. M. Uusitalo, J. Hiltunen, P. Karioja, S. Siitonen, V. Kontturi, R. Myllylä, M. Kinnunen, and I. Meglinski, ” Performance and flow dynamics studies of polymeric optofluidic SERS sensors,” J. Eur. Opt. Soc.-Rapid 10, 15043 (2015).
  13. A. Bykov, T. Hautala, M. Kinnunen, A. Popov, S. Karhula, S. Saarakkala, M. Nieminen, V. V. Tuchin, and I. Meglinski, ”Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage,” J. Biophotonics 1–6 (2015) / DOI 10.1002/jbio.201500130
  14. O. Bibikova, A. Popov, A. Bykov, A. Prilepskii, M. Kinnunen, K. Kordas, V. Bogatyrev, N. Khlebtsov, S. Vainio,  and V. Tuchin, “Optical properties of plasmon-resonant pristine and silica-coated nanostars used for cell imaging,“ Journal of Biomedical Optics, 20(7):076017 (2015).
  15. M.S. Wróbel, A.P. Popov, A.V. Bykov, M. Kinnunen, M. Jędrzejewska-Szczerska, V.V. Tuchin, “Measurements of fundamental properties of homogeneous tissue phantoms,” Journal of Biomedical Optics, 20(4), 045004 (2015).
  16. M. Kinnunen, A. Karmenyan, “Overview of single-cell elastic light scattering techniques,” Journal of Biomedical Optics, 20(5), 051040 (2015).
  17. M. Kinnunen, “A pulsed photoacoustic technique for studying red blood cell sedimentation,” Journal of Biomedical Photonics and Engineering, 1(1), 81-89 (2015).
  18. K. Lee , M. Kinnunen , A.E. Lugovtsov , A.V. Priezzhev, A.V. Karmenyan , “Optical study of the dynamics and deformation of erythrocytes in the flow” Optoelectronics, Instrumentation and Data Processing, 50(5), 519-524 (2014).
  19. V. O. Korhonen, T. S. Myllylä, M.Yu. Kirillin, A. Popov, A. Bykov, A.V. Gorshkov, E.A. Sergeeva, M. Kinnunen, V. Kiviniemi,” Studies of light propagation in optical sensing of the cerebral cortex of the human brain”, Journal of Selected Topics in Quantum Electronics, 20(2) 7100310 (2014).
  20. T. Takalokastari, E. Alasaarela, M. Kinnunen, and T. Jämsä, ”Quality of wireless electrocardiogram signal during physical exercise,” IEEE Journal of Biomedical and Health Informatics, 18(3), 1058-1064 (2014).
  21. E. Warpenius, E. Alasaarela, H. Sorvoja, and M. Kinnunen, ”A mobile user-interface for elderly care from the perspective of relatives,” Informatics for Health and Social Care, early online, 1-12 (2014), DOI: 10.3109/17538157.2013.879148.
  22. M. Kinnunen, A. Bykov, J. Tuorila, T. Haapalainen, A. Karmenyan, and V. Tuchin, ”Optical clearing at a cellular level,” Journal of Biomedical Optics 19(7), 071409  (2014).
  23. M.S. Wróbel, A.P. Popov, A.V. Bykov, M. Kinnunen, M. Jędrzejewska-Szczerska, V.V. Tuchin, “Multi-layered tissue phantoms for noninvasive optical diagnostics”, J. Innov. Opt. Health Sci. 8(3), 1541005 (2015).
  24. A. Kauppila, M. Kinnunen, A. Karmenyan, and R. Myllylä, ”Measurement of the trapping efficiency of elliptical optical tweezers with rigid and elastic objects,” Applied Optics, 51(23), 5705-5712 (2012).
  25. A. Popov, A. Bykov, S. Toppari, M. Kinnunen, A. Priezzhev, and R. Myllylä, “Glucose sensing in flowing blood and Intralipid by laser pulse time-of-flight and optical coherence tomography techniques”, Journal of Selected Topics in Quantum Electronics, 18(3), 1335-1342 (2012).
  26. M. Kinnunen, A. Kauppila, A. Karmenyan, and R. Myllylä, ”Measurement of elastic light scattering from two optically trapped microspheres and red blood cells in a transparent medium,” Optics Letters 36(18), 3554-3556 (2011).
  27. A. Kauppila, M. Kinnunen, A. Karmenyan, and R. Myllylä, ”Elliptical optical tweezers for trapping a red blood cell aggregate,” Photonics Letters of Poland  3(3), 95-97 (2011).
  28. M. Kinnunen, A. Kauppila, A. Karmenyan, and R. Myllylä, "Effect of the size and shape of a red blood cell on elastic light scattering properties at the single-cell level," Biomed. Opt. Express 2, 1803-1814 (2011).
  29. M. Kinnunen and R. Myllylä, "Application of optical coherence tomography, pulsed photoacoustic technique and time-of-flight technique to detect changes in the scattering properties of a tissue-simulating phantom", Journal of Biomedical Optics 13(2), 024005 (2008).
  30. M. Kinnunen, R. Myllylä, S. Vainio, "Detecting glucose-induced changes in in vitro and in vivo experiments with optical coherence tomography", Journal of Biomedical Optics 13(2), 021111 (2008).
  31. M. Kinnunen, R. Myllylä, T. Jokela, S. Vainio, "In-vitro studies toward non-invasive glucose monitoring with optical coherence tomography", Applied Optics 45(10), 2251-2260 (2006).
  32. M. Kinnunen, Z. Zhao, R. Myllylä, "Glucose-induced changes in the optical properties of Intralipid", Optics and Spectroscopy 101(1), 54-59 (2006).
  33. M. Kinnunen and R. Myllylä, "Effect of glucose on photoacoustic signals at the wavelengths of 1064 and 532 nm in pig blood and Intralipid", Journal of Physics D: Applied Physics 38, 2654-2661 (2005).
  34. M. Kinnunen and E. Alasaarela, "Registering the response of tissues exposed to an interferential electric current stimulation", Acupuncture & Electro-Therapeutics Research 29(3-4), 213-226 (2004).

Conference papers

  1. O. Bibikova, J. Haas, Á. I. López-Lorente, A. P. Popov, A. Bykov, M. Kinnunen, V. V. Tuchin, I. Meglinski, B. Mizaikoff, “Plasmonic nanostars as signal enhancers for surface-enhanced vibrational spectroscopy and optical imaging”, Proc. SPIE 10077, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV, 100770J (2017).

  2. K. Lee, A. Danilina, A. Potkin, M. Kinnunen, A. Priezzhev, and I. Meglinski, ”RBC aggregation dynamics in autologous plasma and serum studied with double channel optical tweezers,” Proc. SPIE, Proc. SPIE. 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 991704 (2016).

  3. A. Bykov, T. Hautala, M. Kinnunen, A. Popov; S. Karhula, S. Saarakkala, M. T. Nieminen, and V. Tuchin, “Optical clearing of articular cartilage: a comparison of clearing agents,” Proc. SPIE 9540, Novel Biophotonics Techniques and Applications III, 95400A (2015).

  4. O. Bibikova, P. Singh, A. Popov, G. Akchurin, I. Skovorodkin, V. Khanadeev, M. Kinnunen, V. Bogatyrev, N. Khlebtsov, S. Vainio, V. Tuchin, “The effect of laser irradiation on living cells incubated with gold nanoparticles”, Proc. SPIE 9340, Plasmonics in Biology and Medicine XII, 934010 (2015).

  5. M. Kinnunen, J. Tuorila, T. Haapalainen, A. Karmenyan, V. Tuchin, and R. Myllylä, “Optical tweezers-assisted measurements of elastic light scattering,” Proc. SPIE, 9031, 90310A (2014). INVITED PAPER

  6. O. Bibikova, A. Popov, A. Bykov, A. Prilepskyii, M. Kinnunen, K. Kordas, V. Bogatyrev, N. Khlebtsov, and V. Tuchin, “Gold nanostructures for OCT imaging of capillary flow,” Proc. SPIE 9129, Biophotonics: Photonic Solutions for Better Health Care IV, 912930 (May 8, 2014).

  7. M. Kinnunen, A. Karmenyan, A. Särkelä, E. Y. Dimova, and T. Kietzmann, ” Low-intensity light  detection methods for selected biophotonic applications,” Proc. SPIE, 9421, 94210D (2014). INVITED PAPER

  8. O. Bibikova, A. Popov, I. Skovorodkin, A. Prilepskyi, T. Pylaev, A. Bykov, S. Staroverov, V. Bogatyrev, V. Tuchin, M. Kinnunen, S. Vainio, K. Kordas, and N. Khlebtsov, “Plasmon-resonant gold nanoparticles with variable morphology as optical labels and drug carriers for cytological research”, in Novel Biophotonic Techniques and Applications II, Vitkin, Amelink, Eds., Proc. SPIE 8801, 880102 (2013).

  9. T. Myllylä, A. Popov, V. Korhonen, A. Bykov, M. Kinnunen, “Optical sensing of a pulsating liquid in a brain-mimicking phantom”, in Diffuse Optical Imaging IV, Taroni, Dehghani, Eds., Proc. SPIE 8799, 87990X (2013).

  10. A.P. Popov, A.V. Bykov, E.V. Khaydukov, A.V. Nechaev, V.Ya. Panchenko, V.A. Semchishen, V.N. Seminogov, A.S. Akhmanov, V.I. Sokolov, M. Kinnunen, V.V. Tuchin, A.V. Zvyagin, “High-resolution deep-tissue optical imaging using anti-stokes nanophosphors”, in Novel Biophotonic Techniques and Applications II, Vitkin, Amelink, Eds., Proc. SPIE 8801, 88010C (2013).

  11. D. Gallego, H. Lamela, M. Wang, J. Hiltunen, M. Kinnunen, and R. Myllylä, “Interferometric polymer optical sensor for intravascular optoacoustic imaging,” Fiber Optic Sensors and Applications IX. Du, Henry, H.; Pickrell, Gary; Udd, Eric; Benterou, Jerry, J.; Mendez, Alexis; Mihailov, Stephen, J.; Wang, Anbo. Proc. SPIE 8370, 83700T (2012).

  12. A. Kauppila, M. Kinnunen, A. Karmenyan, and R. Myllylä, ”Elastic light scattering measurements from multiple red blood cells in elliptical optical tweezers,” Proc. SPIE, Vol. 8097, 80970K (2011).

  13. M. Collins, A. Kauppila, A.V. Karmenyan, L. Gajewski, K. Szewczyk, M. Kinnunen, and R. Myllylä, “Measurements of light scattering from trapped particles,” Proc. SPIE, Vol. 7376, 737619, 2010.

  14. A. V. Bykov, A. P. Popov, M. Kinnunen, T. Prykäri, A. V. Priezzhev, and R. Myllylä, ”Skin phantoms with realistic vessel structure for OCT measurements,”Proc. SPIE 7376, 73760F (2010).

  15. J. Lauri, M. Wang, M. Kinnunen, and R. Myllylä, ”Measurement of microfluidic flow velociy profile with two Doppler optical coherence tomography systems,“ Proc. SPIE, Optical diagnostics and sensing VIII, Vol. 6863, 68630F, 2008.

  16. M. Määttälä, J. Lauri, M. Kinnunen, J. Hast and R. Myllylä, "Fiber-optic biosensor based on self-mixing interferometry", Proc. SPIE 7142, 71420I (2008).

  17. F. Zhang, M. Kinnunen, A. Popov, and R. Myllylä, ”Monte Carlo method for simulating optical coherence tomography signal in homogeneous turbid media,” Proc. SPIE, Advanced Laser Technologies ALT´07, Vol. 7022, 702213, 2008.

  18. M. Kinnunen, S. Tausta, R. Myllylä, and S. Vainio, “Monitoring changes in the scattering properties of mouse skin with optical coherence tomography during an in vivo glucose tolerance test,” Proc. SPIE, Saratov Fall Meeting 2006: Optical Technologies in Biophysics and Medicine VIII, Vol. 6535, 65350B, 2007. INVITED PAPER

  19. M. Kinnunen, and R. Myllylä, “Comparative study of optical coherence tomography, photoacoustic technique, and time-of-flight technique in phantom measurements,” Proc. SPIE, Vol. 6163, Saratov Fall Meeting: Optical Technologies in Biophysics and Medicine VII, September 27-30, 2005, Saratov, Russia, pp. 616304-1 - 616304-13, 2006. INVITED PAPER

  20. M. Kirillin, A. V. Priezzhev, M. Kinnunen, E. Alarousu, Z. Zhao, J. Hast, and R. Myllylä, ”Glucose sensing in aqueous Intralipid suspension with an optical coherence tomography system: experiment and Monte Carlo simulation,” Photonics West, BiOS 2004, Proc. SPIE, Vol. 5325, pp. 164 – 173, 2004.

  21. M. Kinnunen, Z. Zhao, and R. Myllylä, “Effect of Glucose on Optical Properties of Intralipid – Measurements with Photoacoustic and Optical Techniques”, Proceedings of the OSAV’2004, The International Topical Meeting on Optical Sensing and Artificial Vision OSAV’2004, Saint Petersburg 2004, pp. 248 – 255.

  22. M. Kinnunen, A. P. Popov, J. Pluciński, R. Myllylä, and A. V. Priezzhev, “Measurements of glucose content in scattering media with time of flight technique; comparison with Monte Carlo simulations”, Proc. SPIE Vol. 5474, p. 181 – 191, 2004, Saratov Fall Meeting 2003: Optical Technologies in Biophysics and Medicine V; Valery V. Tuchin; Ed.

  23. E. Alarousu, J. Hast, M. Kinnunen, M. Kirillin, R. Myllylä, J. Pluciński, A. Popov, A.V. Priezzhev, T. Prykäri, J. Saarela, and Z. Zhao, “Noninvasive glucose sensing in scattering media using OCT, PAS and TOF techniques”, Proc. SPIE Vol. 5474, pp. 33 – 41, 2004. Saratov Fall Meeting 2003: Optical Technologies in Biophysics and Medicine V; Valery V. Tuchin; Ed.



Last updated: 27.7.2017