Selected publications

 

Reviews:

Nyberg P, Salo T, Kalluri R. (2008). Tumor microenvironment and angiogenesis. Front Biosci. 13:6537-53.

Sorsa T, Tjäderhane L, Konttinen YT, Lauhio A, Salo T, Golub LM, Brown DL, Mäntylä P (2006). Matrix Metalloproteinases: Contribution to pathogenesis, diagnosis and treatment of periodontal inflammation. Ann Med 38:306-321.

Nyberg P, Ylipalosaari M, Sorsa T, Salo T (2006). Trypsins and their role in carcinoma growth. Exp Cell Res 312:1220-1228.

Sorsa T, Tjäderhane L, Salo T (2004). Matrix Metalloproteinases (MMPs) in oral Diseases Review. Oral Diseases 10:311-318.

 

Original articles:

Bello IO, Alanen K, Slootweg PJ, Salo T. (2009). Alpha-smooth muscle actin within epithelial islands is predictive of ameloblastic carcinoma. Oral Oncol. Jan 15. [Epub ahead of print]

Kuula H, Salo T, Pirilä E, Tuomainen AM, Jauhiainen M, Uitto VJ, Tjäderhane L, Pussinen PJ, Sorsa T. (2009). Local and systemic responses in matrix metalloproteinase 8-deficient mice during Porphyromonas gingivalis-induced periodontitis. Infect Immun. 77:850-9.

Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R. (2008). Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor. Exp Cell Res. 314:3292-305.

Bello IO, Vilen ST, Niinimaa A, Kantola S, Soini Y, Salo T. (2008). Expression of claudins 1, 4, 5, and 7 and occludin, and relationship with prognosis in squamous cell carcinoma of the tongue. Hum Pathol. 39:1212-20.

Korpi JT, Kervinen V, Mäklin H, Väänänenf A, Lahtinen M, Läärä E, Ristimäki A, Thomas G, Ylipalosaari M, Aström P, Lopez-Otin C, Sorsa T, Kantola S, Pirilä E, Salo T. (2008). Collagenase-2 (matrix metalloproteinase-8) plays a protective role in tongue cancer. Br J Cancer. 98:766-75.

Vilen ST, Nyberg P, Hukkanen M, Sutinen M, Ylipalosaari M, Bjartell A, Paju A, Haaparanta V, Stenman UH, Sorsa T, Salo T. (2008). Intracellular co-localization of trypsin-2 and matrix metalloprotease-9: possible proteolytic cascade of trypsin-2, MMP-9 and enterokinase in carcinoma. Exp Cell Res. 314:914-26.

Laaksonen M, Suojanen J, Nurmenniemi S, Läärä E, Sorsa T, Salo T. (2008). The enamel matrix derivative (Emdogain) enhances human tongue carcinoma cells gelatinase production, migration and metastasis formation. Oral Oncol. 44:733-42.

Pääkkönen V, Vuoristo JT, Salo T, Tjäderhane L. (2008). Comparative gene expression profile analysis between native human odontoblasts and pulp tissue. Int Endod J. 41:117-27.

Pääkkönen V, Vuoristo J, Salo T, Tjäderhane L. (2007). Effects of TGF-beta 1 on interleukin profile of human dental pulp and odontoblasts. Cytokine 40:44-51.

Pirilä E, Korpi JT, Korkiamäki T, Jahkola T, Gutierrez-Fernandez A, Lopez-Otin C, Saarialho-Kere U, Salo T, Sorsa T. (2007). Collagenase-2 (MMP-8) and matrilysin-2 (MMP-26) expression in human wounds of different etiologies. Wound Repair Regen. 15:47-57.

Bello IO, Soini Y, Slootweg PJ, Salo T. (2007). Claudins 1, 4, 5, 7 and occludin in ameloblastomas and developing human teeth. J Oral Pathol Med. 36:48-54.

Väänänen A, Ylipalosaari M, Parikka M, Kainulainen T, Rehn M, Heljasvaara R, Tjäderhane L, Salo T. (2007). Collagen XVIII modulation is altered during progression of oral dysplasia and carcinoma. J Oral Pathol Med. 36:35-42.

Alho OP, Hannula K, Luokkala A, Teppo H, Koivunen P, Kantola S. (2007). Differential prognostic impact of comorbidity in head and neck cancer. Head Neck 29:913-8.

Alho OP, Teppo H, Mäntyselkä P, Kantola S. (2006). Head and neck cancer in primary care: presenting symptoms and the effect of delayed diagnosis of cancer cases. CMAJ. 174:779-84.

Salo T, Sorsa T, Lindqvist C. (2006). Inhibition of gelatinase activity by cyclic peptides--A support for oral cancer treatment? Oral Oncol. 2006 42:955-6.

Heikkilä P, Suojanen J, Pirilä E, Väänänen A, Koivunen E, Sorsa T, Salo T (2006). Human tongue carcinoma growth is inhibited by selective antigelatinolytic peptides. Int J Cancer 118: 2202-2209.

Sudhakar A, Nyberg P, Keshamouni VG, Mannam AP, Li J, Sugimoto H, Cosgrove D, Kalluri R (2005). Human α1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by α1β1 integrin. J Clin Invest 115: 2801-2810.

Nyberg P, Heikkilä P, Sorsa T, Luostarinen J, Heljasvaara R, Stenman U-H, Pihlajaniemi T, Salo T (2003). Endostatin inhibits human tongue carcinoma cell invasion and intravasation and blocks the activation of matrix metalloprotease-2, -9 and -13. J Biol Chem 278: 22404-22411.

Moilanen M, Pirilä E, Grenman R, Sorsa T, Salo T (2002). Expression and regulation of collagenase-2 (MMP-8) in head and neck squamous cell carcinomas. J Pathol 197: 72-81.

Kantola S, Jokinen K, Hyrynkangas K, Mäntyselkä P, Alho OP. (2001). Detection of tongue cancer in primary care. Br J Gen Pract. 51106-11.

Alho OP, Kantola S, Pirkola U, Läärä E, Jokinen K, Pukkala E. (1999). Cancer of the mobile tongue in Finland--increasing incidence, but improved survival. Acta Oncol. 38:1021-4.

Sutinen M, Kainulainen T, Hurskainen T, Vesterlund E, Alexander JP, Overall CM, Sorsa T and Salo T (1998). Expression of matrix metalloproteinases (MMP-1 and –2) and their inhibitors (TIMP-1, -2 and –3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis. Br J Cancer 77:2239-2245.

Tjäderhane L, Larjava H, Sorsa T, Uitto VJ, Larmas M and Salo T (1998). The activation and function of host matrix metalloproteinases in dentin matrix breakdown in caries lesions. J Dent Res 77:1622-1629.

Tjäderhane L, Salo T, Larjava H, Larmas M and Overall CM (1998). A novel organ culture method of human odontoblasts in vitro: gelatinase expression by odontoblasts is differentially regulated by TGF-beta1. J Dent Res 77:1486-1496.

Hanemaaijer R, Sorsa T, Konttinen YT, Ding Y, Sutinen M, Visser H, van Hinsbergh VWM, Helaakoski T, Kainulainen T, Rönkä H, Tschesche H and Salo T (1997). Matrix metalloproteinase-8 is expressed in rheumatoid synovial fibroblasts and endothelial cells. J Biol Chem 272:31504-31509.

Sorsa T, Salo T, Koivunen E, Tyynelä J, Konttinen YT, Bergmann U, Tuuttila A, Niemi E, Teronen O, Heikkilä P, Tschesche H, Leinonen J, Osman S and Stenman U-H (1997). Activation of type IV procollagenases by human tumor-associated trypsin-2. J Biol Chem 272:21067-21074.