Huikuri Heikki

Cardiology Research Group

Group leader : professor Heikki Huikuri

 

Background and significance

The main focus of cardiology research team is on prediction and prevention of sudden unexpected cardiac death (SCD) by integrating data obtained from comprehensive phenotyping and genotyping of the risk of SCD in various population samples, e.g. in large national cohorts including 25.000 middle-aged subjects with a long follow-up. The risk factors of SCD will also be analysed in patients with coronary artery disease (CAD) in ARTEMIS project including 2000 CAD patients with and without type 2 diabetes and in the FinGesture study which is a prospective case-control study including currently 4200 victims of ischemic SCD verified by autopsy (cases) and 4000 survivors of an acute coronary event (controls).

Future goals

We anticipate that this multidisciplinary project combining the expertise in clinical cardiology, biomedical engineering, together with national and international collaborators will bring more insight into the background of fatal arrhythmic events and ultimately would benefit the development of new targeted strategies to prevent premature sudden cardiac death at the population level.

Research funding

  • 2008, Sigrid Juseliuksen Säätiö, Sydänpysähdyksen ennustaminen ja ehkäisy

  • 2009, Sigrid Juseliuksen Säätiö, Sydänpysähdyksen ennustaminen ja ehkäisy

  • 2010, Sigrid Juseliuksen 5-vuotinen suurapuraha, Deep Phenotyping in Combination with Genetic Profiles in Sudden Cardiac Death

  • 2011-2015, Sigrid Juseliuksen 5-vuotinen suurapuraha, Deep Phenotyping in Combination with Genetic Profiles in Sudden Cardiac Death

  • 2008-2010, Suomen Kardiologinen Seura, Kantasoluhoito sydäninfarktissa

  • 2008-2011, Suomen Akatemia, Kantasoluhoito kroonisessa sydäninfarktissa

  • 2007-2012, Tekes, Innovation to reduce cardiovascular complications of diabetes at the intersection

Research group members

Post-doctoral researchers:

  • Juhani Junttila, docent

  • Juha Perkkiömäki, docent

  • Timo Mäkikallio, docent

  • Mikko Tulppo, docent

  • Arto Hautala, docent

  • Antti Kiviniemi, docent

  • Olli Anttonen, docent

  • Kari Kaikkonen, MD

  • Jani Tikkanen, MD

  • Aapo Aro, MD

  • Olli-Pekka Piira, MD

  • Mirja Peltola, PhD

  • Tuomas Kenttä, PhD

  • Eeva Hookana, PhD

PhD-students:

  • Juha Saarinen

  • Samuli Lepojärvi

  • Henri Terho

  • Antti Eranti

  • Arttu Holkeri

Other staff:

  • Pirkko Huikuri, study nurse

  • Päivi Koski, study nurse

  • Päivi Kastell, laboratory technician

  • Anne Lehtinen, study secretary

Most important collaborators

National:  Professor Tapio Seppänen, Technical Faculty, University of Oulu,  Professor Veikko Salomaa, and  Professor Paul Knekt,  Institute of Health and Welfare, Helsinki, Finland.

International: Professor Derek Exner, University of Calgary, Canada and Professor Dan Arking, John Hopkins University, USA.

 

  

Last updated: 7.3.2017