The clinical service actively pursues improvement of surgical results. It applies the relevant scientific advances to clinical practice. The main clinical goal has been minimally invasive neurosurgery featuring both the technology and its assessment. For more information, see: Innovative Clinic Model.
The Oulu School of Minimally Invasive Neurosurgery
The major focus of research has led to the Oulu School of Minimally Invasive Neurosurgery.
The development of surgical techniques has progressed from stereotaxy and intraoperative ultrasound imaging, to open stereotactic surgery, to the neuronavigator, and most recently to the intraoperative MRI and CT.
The Neurosurgical Research Unit
The Neurosurgical Research Unit (NRU) features a core group of researchers with respective scientific personnel and facilities in several locations in the hospital and university, and elsewhere nationally.
Clinical faculty participates in NRU activities.
Areas of Specific Research
The research program consists of clinical patient follow-up studies, neurosurgical technology, molecular biology and assessment of health care technology.
Selected Scientific Works
SELECTED FACULTY PUBLICATIONS:
PH.D. THESES (By department faculty, all at the University of Oulu)
Heikkinen, Esa (1976) Cerebrospinal fluid cyclic AMP: A clinicoexperimental study
Koivukangas, John (1984) Ultrasound imaging in operative neurosurgery: An experimental and clinical study with special reference to ultrasound holographic B (UHB) imaging
Kumpulainen, Timo (1986) Demonstration of carbonic anhydrases I and II by immunohistochemical and radioimmunoassay techniques with special emphasis on the nervous system. & Department of Anatomy
Heiskari, Matti (1988) Operative treatment for radiculopathy and myelopathy in cervical degenerative disc diseases: With special reference to diagnostic and postoperative somatosensory evoked potential studies
Rönty, Hannu (1988) Cerebral trauma: A clinical, computed tomography, quantitative EEG, blood circulation isotope and neuropsychological follow-up study
Sajanti, Juha (1999) Meningeal fibrosis after subarachnoid haemorrhage : a clinical and experimental study
Yrjänä, Sanna (2005) Implementation of 0.23 T magnetic resonance scanner to perioperative imaging in neurosurgery
Erola, Tuomo (2006) Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: A clinical study. & Department of Neurology.
Tetri, Sami (2009) Factors affecting outcome after primary intracerebral hemorrhage. & Department of Neurology.
JOINT PH.D. THESES (University of Oulu)
Alasaarela, Esko (1983) Ultrasound holographic B (UHB) imaging: A theoretical analysis, computer simulation and preliminary experiments. Department of Electrical Engineering
Ylitalo, Juha (1987) Ultrasound tomography. Department of Electrical Engineering
Zhengdi, Qin (1988) Frequency domain compensation principle in acoustic holography and circular array imaging using linear array approach. Department of Electrical Engineering
Tervonen, Osmo (1988) Ultrasound of the lumbar intervertebral disc and spinal canal. Department of Diagnostic Radiology
Koivukangas, Pirjo (1993) A two-wave MIMIC model for the construction of a health status index based on the health production function: With special reference to the assessment of neurosurgical treatment of brain tumor patients. Department of Economics
Ying, Xiaoyou (1995) Digital imaging based on measurements and analyses in quantitative biomedical research at cellular and microvascular levels. & Departments of Physical Sciences / Division of Biophysics, and Electrical Engineering
Ohinmaa, Arto (1997) Indexing health-related quality of life: A comparison of preference-weighted and unweighted indexes. & Department of Economics
Oikarinen, Jarkko (1999) Accelerating direct volume rendering using seed filling in the lattice view. & Departments of Information Processing Science, Diagnostic Radiology, and Biomedical Engineering Program
Mainio, Arja (2005) Depressive and anxious symptomatology in relation to a primary brain tumor. & Department of Psychiatry.
Kokkonen, Salla-Maarit (2009) MRI of intracranial tumours in adults: Oedema-attenuated inversion recovery MR sequence in low-field MRI, diffusion-weighted MRI and BOLD fMRI. & Department of Diagnostic Radiology.
Jartti, Pekka (2010) Computed tomography in subarachnoid haemorrhage: Studies on aneurysm localization, hydrocephalus and early bleeding. & Department of Diagnostic Radiology.
Schiffbauer, Hagen (1998) Neuronavigation in brain tumor surgery - Clinical beta-phase of the Oulu Neuronavigator System. & Westfälische Wilhelms-Universität, Münster, Germany
OTHER RELEVANT PH.D. THESES
Alakuijala, Jyrki: (2001) Algorithms for modeling anathomic and target values in image-guided neurosurgery and radiotherapy. Department of Electrical Engineering
Ojala, Risto: (2002) MR-guided interventions at 0.23T. Department of Diagnostic Radiology
DOCTORAL THESES IN THE MAKING
Niemelä, Asko: Quality of life in outcomes analysis of brain tumor treatment. & Department of Psychiatry
Koskelainen, Tatu: Assessment of neuromodulation for treatment of pain
Louhisalmi, Yrjö: Surgical robotics. & Department of Mechanical Engineering
Katisko, Jani: Intraoperative imaging
Tuominen, Juho: Neurosurgical intraoperative MRI
Heula, Anna-Leena: Moleculat biology of subdural hematoma
Salokorpi, Niina: Molecular biology and imaging of meningioma
Raappana, Antti: Pituitary adenoma. & Department of Otorhinolaryngology
Koivukangas, Tapani: Neuronavigator accuracy. & Department of Mechanical Engineering
Kauppinen, Mikko: Management of severe head injuries
JOINT LICENSIATE THESES
Koivukangas, Pirjo (1990) Application of the analysis of demand for health to the construction of a MIMIC-disability index: With special reference to the measurement of surgical management of brain tumors. Department of Economics.
Louhisalmi, Yrjö (1992) Neurosurgical localization arm. Department of Mechanical Engineering
Katisko, Jani (2004) Optically neuronavigated ultrasonography in intraoperative magnetic resonance imaging environment. Department of Physics
JOINT MASTER´S THESES
Louhisalmi, Yrjö (1987) Computer assisted method for laser guidance in stereotactic neurosurgery. Department of Mechanical Engineering
Oikarinen, Jarkko (1992) Visualization system for neuronavigator. Department of Electrical Engineering
Alakuijala, Jyrki (1992) System interfaces and control for neurosurgical workstation. Department of Electrical Engineering
Helminen, Hannu (1993) Geometric modeling of neuronavigator and intraoperative registration of diagnostic volumetric imaging. Department of Electrical Engineering
Kukkonen, Jaana (1994) Activity based costing in an academic neurosurgical department. & Department of Economics
Pentikäinen, Tuomo (1995) Economic evaluation of health care as method to control market failure. & Department of Economics (Helsinki)
Anttila, Petri (1996) The use of cost analysis in the economic assessment of hospital activity. & Department of Economics
Katisko, Jani (1997) Development of endoscopic ultrasound transducer for neurosurgery. & Department of Physical Sciences, Biophysics
Kanervo, Jari (1997) The development of total quality control at an academic neurosurgical department. & Department of Economics
Koivukangas, Tapani (2008) A phantom and protocol for accuracy assessment of surgical navigators. & Department of Mechanical Engineering
Hertel, Stefan (2010) A patient positioning device for intraoperative MRI. & Departments of Mechanical Engineering, and Neurosurgery, University of Minnesota, Minneapolis MN, USA
Last Updated 14 February 2001