Mechanisms of Organogenesis

Seppo Vainio, Ph.D.

Project leader
Prof. Seppo Vainio, Ph.D.

Laboratory of Developmental Biology, Oulu Center for Cell-Matrix Research,
Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of Oulu

Mailing address
P.O.Box 5000, FIN-90014 University of Oulu, Finland

Street address
Aapistie 5A, Biocenter Oulu, 4th floor, 90220 Oulu, Finland

Tel. +358-(0)294 486084,
e-mail: seppo.vainio (at)

Focus area spearhead project web page:

About the project

The problem of how multipotent cells assemble in a spatially and temporally controlled manner to well organized three dimensional functional structures during organogenesis is a major challenge. The process is directed by cell-cell and tissue interactions mediated by the associated signals exchanged by the cells. The fine details how this leads to well orchestrated anatomical structures is a challenge in all biological systems. The capacity to edit the genome also in human cells has set the stage to reveal the mechanistic details. Our project targets the fundaments of normal and the deregulated organ assembly programs. The project is part of the Finnish Centre of Excellence Programme funded by the Academy of Finland (Centre of Excellence Grant 2012 - 2017, 251314)

Project details

  1. Background and Significance
  2. Recent Progress
  3. Future Goals
  4. Publications 2016-
  5. Patents 2016
  6. Research Group Members
  7. National and International Activities

Last updated: 15.10.2018