A number of rare genetic variants identified in the background of sudden cardiac deaths associated with obesity and hypertension

The University of Oulu’s Cardiology Research Group identified several rare genetic variants in victims of sudden death caused by hypertension- or obesity-related cardiac hypertrophy. The findings suggest that, in addition to lifestyle, genes may also play a role in hypertension- and obesity-related cardiac hypertrophy.

The authors include several Biocenter Oulu researchers from different research groups.

Genetic contributions to the expression of acquired causes of cardiac hypertrophy in non-ischemic sudden cardiac death victims by Lauri Holmström, Katri Pylkäs, Anna Tervasmäki, Juha Vähätalo, Katja Porvari, Lasse Pakanen, Kari S. Kaikkonen, Juha S. Perkiömäki, Antti M. Kiviniemi, Risto Kerkelä, Olavi Ukkola, Robert J. Myerburg, Heikki V. Huikuri & Juhani Junttila. Published in Scientific Reports Sci Rep 11, 11171 (2021). 

Link to the publication.

Last updated: 4.6.2021