An article in Nature Communications by the Winqvist group

An article from Robert Winqvist´s group and Helmut Pospiech with Jenni Nikkilä, Ann Parplys and Katri Pylkäs with shared first authors was published in Nature Communications on Oct 24. This study provides a new mechanism for early stages of breast cancer development that may also apply to other heterozygous homologous recombination signalling pathway gene mutations in hereditary cancer predisposition.

Heterozygous mutations in PALB2 cause DNA replication and damage response defects. Nikkilä J, Christin Parplys A, Pylkäs K, Bose M, Huo Y, Borgmann K, Rapakko K, Nieminen P, Xia B, Pospiech H, Winqvist R. Nat Commun. 2013 Oct 24;4:2578. doi: 10.1038/ncomms3578.

Last updated: 2.9.2016