Publications

Taina K. Lajunen (née Korhonen), PhD

27 peer reviewed scientific publications
11 publications in journals ranked within the highest 10th percentile of their reference group
20 publications in PubMed

PEER-REVIEWED SCIENTIFIC ARTICLES

  1. Selman C, Korhonen TK, Brünger L, Hill WG, Speakman JR. Thermoregulatory responses of two mouse Mus musculus strains selectively bred for high and low food intake. J Comp Physiol B 2001; 171(8): 661-8.
     
  2. Törmakangas L, Erkkilä L, Korhonen T, Tiirola T, Bloigu A, Saikku P, Leinonen M. Effects of repeated Chlamydia pneumoniae inoculations on aortic lipid accumulation and inflammatory response in C57BL/6J mice. Infect Immun 2005; 73(10): 6458-66.
     
  3. Harju TH, Leinonen M, Nokso-Koivisto J, Korhonen T, Räty R, He Q, Hovi T, Mertsola J, Bloigu A, Rytilä P, Saikku P. Pathogenic bacteria and viruses in induced sputum or pharyngeal secretions of adults with stable asthma. Thorax 2006; 61(7): 579-84.
     
  4. Korhonen T, Grauling-Halama S, Halama N, Silvennoinen-Kassinen S, Leinonen M, Saikku P. Rapid genotyping of lipopolysaccharide-binding protein (LBP) C(1341)-->T (Leu(436)-->Phe) polymorphism by LightCycler real-time PCR. J Immunol Methods 2006; 317(1-2): 171-4.
     
  5. Poikonen K, Lajunen T, Silvennoinen-Kassinen S, Paldanius M, Leinonen M, Saikku P. Susceptibility of human monocyte-macrophages to Chlamydia pneumoniae infection in vitro is highly variable and associated with levels of soluble CD14 and C. pneumoniae IgA and human HSP-IgG antibodies in serum. Scand J Immunol 2008; 67(3): 279-84.
     
  6. Lajunen T, Vikatmaa P, Ikonen T, Lepäntalo M, Lounatmaa K, Sormunen R, Rantala A, Leinonen M, Saikku P Comparison of polymerase chain reaction methods, in situ hybridization, and enzyme immunoassay for detection of Chlamydia pneumoniae in atherosclerotic carotid plaques. Diagn Microbiol Infect Dis 2008; 61(2): 156-64.
     
  7. Rantala A, Lajunen T, Juvonen R, Bloigu A, Silvennoinen-Kassinen S, Peitso A, Saikku P, Vainio O, Leinonen M. Mannose-binding lectin concentrations, MBL2 polymorphisms, and susceptibility to respiratory tract infections in young men. J Infect Dis 2008; 198(8): 1247-53.
     
  8. Lajunen T, Vikatmaa P, Bloigu A, Ikonen T, Lepäntalo M, Pussinen PJ, Saikku P, Leinonen M. Chlamydial LPS and high-sensitivity CRP levels in serum are associated with an elevated body mass index in patients with cardiovascular disease. Innate Immun 2008; 14(6): 375-82.
     
  9. Poikonen K, Lajunen T, Silvennoinen-Kassinen S, Leinonen M, Saikku P. Effects of CD14, TLR2, TLR4, LPB, and IL-6 gene polymorphisms on Chlamydia pneumoniae growth in human macrophages in vitro. Scand J Immunol 2009; 70(1): 34-9.
     
  10. Rantala A, Lajunen T, Juvonen R, Bloigu A, Paldanius M, Silvennoinen-Kassinen S, Peitso A, Vainio O, Leinonen M, Saikku P. Low mannose-binding lectin levels and MBL2 gene polymorphisms associate with Chlamydia pneumoniae antibodies. Innate Immun 2011;17(1):35-40.
     
  11. Vikatmaa P, Lajunen T, Ikonen TS, Pussinen PJ, Lepäntalo M, Leinonen M, Saikku P. Chlamydial lipopolysaccharide (cLPS) is present in atherosclerotic and aneurysmal arterial wall-cLPS levels depend on disease manifestation. Cardiovasc Pathol 2010;19(1):48-54.
     
  12. Poikonen K, Lajunen T, Silvennoinen-Kassinen S, Leinonen M, Saikku P. Quantification of Chlamydia pneumoniae in cultured human macrophages and HL cells: comparison of real-time PCR, immunofluorescence and ELISA methods. APMIS 2010; 118(1): 45-8.
     
  13. Jounio U, Rantala A, Bloigu A, Juvonen R, Lajunen T, Silvennoinen-Kassinen S, Peitso A, Vainio O, Harju T, Saukkoriipi A, Leinonen M. Smoking status interacts with the association between mannose-binding lectin serum levels and gene polymorphism and the carriage of oropharyngeal bacteria. Hum Immunol 2010; 71(3): 298-303.
     
  14. Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurðsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Thorand B, Tichet J, Tönjes A, Tuomi T, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zeggini E, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC; DIAGRAM Consortium; GIANT Consortium; Global BPgen Consortium, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H, Wilson JF; Anders Hamsten on behalf of Procardis Consortium; the MAGIC investigators, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, Barroso I. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010; 42(2): 105-16.
     
  15. Rantala A, Lajunen T, Juvonen R, Bloigu A, Paldanius M, Silvennoinen-Kassinen S, Peitso A, Vainio O, Leinonen M, Saikku P. Chlamydia pneumoniae infection is associated with elevated body mass index in young men. Epidemiol Infect 2010; 138(9): 1267-73.
     
  16. Pradhan-Palikhe P, Vikatmaa P, Lajunen T, Palikhe A, Lepäntalo M, Tervahartiala T, Salo T, Saikku P, Leinonen M, Pussinen PJ, Sorsa T. Elevated MMP-8 and decreased myeloperoxidase concentrations associate significantly with the risk for peripheral atherosclerosis disease and abdominal aortic aneurysm. Scand J Immunol. 2010; 72(2): 150-7.
     
  17. Rantala A, Lajunen T, Juvonen R, Silvennoinen-Kassinen S, Peitso A, Vainio O, Saikku P, Leinonen M. Association of IL-6 and IL-6R gene polymorphisms with susceptibility to respiratory tract infections in young Finnish men. Hum Immunol 2011; 72(1): 63-8.
     
  18. Rantala A, Lajunen T, Juvonen R, Paldanius M, Silvennoinen-Kassinen S, Peitso A, Vainio O, Leinonen M, Saikku P. Interleukin-6 -174 G/C promoter polymorphism is associated with persistence of Chlamydia pneumoniae antibodies in young men. Scand J Immunol 2011; 74(1): 95-9.
     
  19. Lajunen T, Bloigu A, Paldanius M, Pouta A, Laitinen J, Ruokonen A, Hartikainen AL, Savolainen M, Herzig KH, Leinonen M, Saikku P, Järvelin MR. The association of body mass index, waist and hip circumference, and waist-hip ratio with Chlamydia pneumoniae IgG antibodies and high-sensitive C-reactive protein at 31 years of age in Northern Finland Birth Cohort 1966. Int J Obes (Lond) 2011; 35(12): 1470-8.
     
  20. Lajunen TK, Purhonen AK, Haapea M, Ruokonen A, Puukka K, Hartikainen AL, Savolainen MJ, Morin-Papunen L, Tapanainen JS, Franks S, Järvelin MR, Herzig KH. Full-length visfatin levels are associated with inflammation in women with polycystic ovary syndrome. Eur J Clin Invest 2012; 42(3): 321-8.
     
  21. Lajunen TK, Jaakkola JJK, Jaakkola MS. Influence of heredity on asthma continues into adulthood. J Allergy Clin Immunol 2013 Mar;131(3):916-18. doi: 10.1016/j.jaci.2012.10.035. Epub 2012 Dec 11. IF 11.248
     
  22. Paaso EM, Jaakkola MS, Lajunen TK, Hugg TT, Jaakkola JJ. The Importance of Family History in Asthma during the First 27 Years of Life. Am J Respir Crit Care Med. 2013 Sep 1;188(5):624-6. doi: 10.1164/rccm.201212-2236LE. IF 11.986
     
  23. Lajunen TK, Jaakkola JJ, Jaakkola MS. The Synergistic Effect of Heredity and Exposure to Second-hand Smoke on Adult-onset Asthma. Am J Respir Crit Care Med. 2013 Oct 1;188(7):776-82. doi: 10.1164/rccm.201304-0773OC. IF 11.986
     
  24. Lajunen TK, Jaakkola JJ, Jaakkola MS. Interleukin 6 SNP rs1800797 associates with the risk of adult-onset asthma. Genes Immun. 2016 Apr;17(3):193-8. doi: 10.1038/gene.2016.8. Epub 2016 Mar 3. IF 2.524
     
  25. Lajunen TK, Jaakkola JJK, Jaakkola MS. Interleukin 6 polymorphisms modify the effects of smoking on the risk of adult asthma. J Allergy Clin Immunol 2018;141(2);799–802.e9. doi: 10.1016/j.jaci.2017.09.011. IF 14.110 (Q1). JUFO 3.
     
  26. Wang YC, Jaakkola M, Lajunen T, Lai CH, Jaakkola J. Asthma-COPD Overlap Syndrome (ACOS) among Subjects with Newly Diagnosed Adult-Onset Asthma. Allergy. 2018 Jul;73(7):1554-1557. doi: 10.1111/all.13459. IF 6.771 (Q1). JUFO 2.
     
  27. Jaakkola JJK, Hernberg S, Lajunen T, Sripaiboonkij P, Malmberg P, Jaakkola MS. Smoking and lung function among adults with newly-onset asthma. BMJ Open Resp Res 2019;6:e000377. doi:10.1136/bmjresp-2018-000377. JUFO 1. 
     

NON-REVIEWED SCIENTIFIC ARTICLES

Unrefereed journal articles

  1. Lajunen TK, Jaakkola JJK, Jaakkola MS. Interleukiini 6 (IL-6) polymorfismit muovaavat tupakoinnin vaikutusta astmariskiin. Best Practice 2018 May;6-9.
     

THESES

Lajunen T. Persistent Chlamydia pneumoniae infection, inflammation, and innate immunity. Acta universitatis Ouluensis D1000, Oulu University Press 2008; doctoral dissertation (article)

Korhonen T. CD 14- ja IL-10-promoottoripolymorfismit sekä Chlamydia pneumoniae -infektio sydäninfarktipotilailla , 2002; Master’s thesis

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Last updated: 30.10.2019