BCO projects 2024-2027

14 research projects to the Biocenter Oulu for a period of 2024 – 2027 (in alphabetical order).


  1. Ala-Korpela, Mika, and Mäkinen, Ville-Petteri: Innovative multi-domain metabolomics paradigm to disrupt metabolic health profiling and to improve cardiometabolic disease prevention
  2. Chen, Zhi: The essential role of Th17/Treg cells in inflammation and tumorigenesis
  3. Eklund, Lauri and Kiviniemi, Vesa: Waste clearance in the brain: Pathophysiology in Alzheimer’s disease and novel treatment strategies
  4. Huang, Jian-An and Farrahi, Vahid: Digital Raman assay for single-molecule protein sequencing in single live cells
  5. Karppinen (Koivunen), Peppi: Oxygen and 2-oxoglutarate sensing enzymes as novel therapeutic targets in metabolic, neurological and other disease
  6. Kietzmann, Thomas: Beyond hypoxia-inducible factors: New molecules interacting in hypoxia-signaling and metabolism
  7. Lehtiö, Lari: Activation mechanisms and inhibition of human mono-ADP-ribosyltransferases
  8. Manninen, Aki and Wei, Gong-Hong: The ECM control of the prostate cancer genome
  9. Pirinen, Eija and Herzig, Karl-Heinz: Mitochondrial targeting strategies for the treatment of obesity and metabolic diseases
  10. Pylkäs, Katri: Deciphering inherited breast cancer susceptibility- Integrating diagnostic and novel genomic approaches
  11. Ruddock, Lloyd: Identification and molecular characterization of novel pathways for disulfide formation
  12. Saarakkala, Simo and Jansson Miia: Novel Raman-based reagent-free diagnostics for arthritic disease
  13. Tapiainen, Terhi and Reunanen, Justus: Gut microbiome in obesity from birth to adulthood
  14. Tiulpin, Aleksei, Tikkanen, Jani and Nevalainen, Mika: Low-cost screening for future cardiovascular disease incidence with opportunistic CT