Spearhead projects – Lifelong health University of Oulu directs strategic research funding for multidisciplinary, internationally reviewed 4-year-projects. The spearhead projects related to the research focus area Lifelong health are organized under the focus institute Biocenter Oulu. 2022 – 2025 Safe biomonitoring by bioICT integrated wearables 2020 – 2023 Cellular Compartments and New Molecules Interacting in Hypoxia-Signaling and Associated Diseases 2020 – 2023 Cellular oxygen sensors and other 2-oxoglutarate-dependent enzymes as novel treatment targets for diseases 2020 – 2023 Environmental xenosensor PXR as a disease mechanism and therapeutic target in metabolic diseases 2020 – 2023 Extensive molecular profiling of systemic metabolism to understand and prevent cardiometabolic diseases 2020 – 2023 Genetic causes and molecular mechanisms of myocardial fibrosis 2020 – 2023 Inherited breast cancer susceptibility: novel factors, cellular mechanisms and disease modelling 2020 – 2023 Integrin Signaling and Transcriptional Networks in Cancer 2020 – 2023 Interventions and Contextual Understanding for Low Back Pain Research 2020 – 2023 Key enzyme regulators of the hypoxia response and collagen synthesis as therapeutic targets 2020 – 2023 Molecular and environmental basis for asthma in a changing climate 2020 – 2023 Neuro-ocular clearance pathways - Mechanisms and clinical applications 2020 – 2023 Secreted vesicles of the human intestinal microbiota in health and disease 2020 – 2023 Structural biology of the formation and disease of the multilayered myelin membrane 2020 – 2023 Structure, Function and Inhibition of Human ADP-ribosyltransferases
2020 – 2023 Cellular Compartments and New Molecules Interacting in Hypoxia-Signaling and Associated Diseases
2020 – 2023 Cellular oxygen sensors and other 2-oxoglutarate-dependent enzymes as novel treatment targets for diseases
2020 – 2023 Environmental xenosensor PXR as a disease mechanism and therapeutic target in metabolic diseases
2020 – 2023 Extensive molecular profiling of systemic metabolism to understand and prevent cardiometabolic diseases
2020 – 2023 Inherited breast cancer susceptibility: novel factors, cellular mechanisms and disease modelling
2020 – 2023 Key enzyme regulators of the hypoxia response and collagen synthesis as therapeutic targets