Polyelectrolyte multilayer film as a platform for developing sensors

Dr. Anton Sadovoy
Lecturer's institute: 
Institute of Materials Research and Engineering, A*STAR, Singapore
29.11.2018 10:00 to 30.11.2018 14:00

Time: 10:00 - 14:00 (both days)

Place: TS335 (both days)

Credits: 2-3 ECTS (including written exam)



Chemo-optical responsive materials like fluorescent dyes are very useful sensing tools for in vivo measurements of physiological (physicochemical) properties in cell biology and bio-medical imaging applications. Today many type dyes sensitive to pH, temperature, oxygen, metal ions, heavy metal ions and etc. can be purchased commercially. But high solubility in water and toxic issues in some of cases cause contaminations of an analyte and health issues of cells or animal spices during a test what doesn’t allow to utilise the sensors on a full power. Here I would like to present our 10 years experience of designing and developing an encapsulation technology based on multilayer polyelectrolyte membrane. The technology aims to encapsulate the dyes in the membrane shell to protect measuring environment from contamination as well as allows them to interact with analyte. Here we discuss microcapsules and imprinted films encapsulated approaches developed by our group and I will demonstrate them applications in in vivo sensing of physiology of small aquatics organisms and monitoring of packaged food freshness.

Lectures agenda (10 hours)

  1. Introduction to polyelectrolyte polymers
  2. Polyelectrolyte multilayers (PM) films
  3. Polyelectrolyte multilayer (PM) capsules
  4. Tuning and measuring PM capsules properties
  5. Microencapsulated sensors for in vivo bio-imaging
  6. Future of microencapsulated sensors
  7. Nanoimprint lithography for imprinting PM films – “Chambers”
  8. Properties of PM chambers
  9. Membrane Film Sensors for food freshness monitoring
  10. Commercialisation of membrane film sensors in food industry

Last updated: 26.10.2018