Animals in Laboratory animal centre

Mice and rats

A limited number of regular mice and rat strains are bred in the Laboratory Animal Centre. The strains are selected based on the use volume, and strains that are used less or that are rare will be ordered from external suppliers.

 

Mouse and rat strains bred and maintained in KEKS

Species

Strain

Siitostusmuoto

Origin

Microbiological status

Mouse

Crl:CD1(ICR)

Outbred

Charles River, Germany

Barrier

Mouse

C57BL/6NCrl

Inbred

Charles River, Germany

Barrier

Mouse

FVB/NCrl

Inbred

Charles River, Germany

Barrier

Mouse

C3H/HeNCrl

Inbred

Charles River, Italy

Barrier

 

 

 

 

 

Rat

Crl:CD(SD)

Outbred

Charles River, Germany

Conventional

Outbred strains are produced in a manner that ensures a maximum range of variation in the genome between individuals. The strains are renewed every three years in order for the strain to remain close to the original and to maintain the outbred quality.

Inbred strains are produced by mating siblings with each other for a minimum of 20 generations, after which the animals are genetically close to identical. The inbred strains are renewed approximately every two years in order for them to remain similar to the original strain.

F1-hybrids are the first generation born from crossing two inbred strains. In the acronym, the strain identification number of the mother is labelled first and the strain identification number of the father is second.

 

Rabbits

KEKS acquires rabbits from well-known international animal producers based on researcher orders. Since the premises for experiments conducted with rabbits are limited, arrangements must be negotiated with KEKS personnel well in advance of experiments.

 

Large animals: pigs and sheep

Pigs and sheep are acquired from contract farms based on researcher orders. The pigs are crosses between landrace pigs and the sheep are, e.g., Finnish landrace sheep or Åland sheep. Maintaining large animals on the KEKS premises is very restricted, and the experiment arrangements must be negotiated well in advance.

 

Last updated: 30.12.2016