Northern Finland Birth Cohort
The University of Oulu -owned Northern Finland Birth Cohort is the world’s largest collection of data from early pregnancy until adult senescence, including almost every aspect of basic, epidemiologic and clinical data. Study. The data consists a continuously expanding collection of genetic, epigenetic, molecular and clinical data from 12 058 newborn enrolled in 1966 and from 9 432 newborn enrolled in 1986, followed up by now for 46 years for the 1966 cohort and up to 15/16 years for the 1986 cohort. The next major analysis will be a 32-year time point for the NFBC1986 cohort in 2017-2018. The
NFBC was initiated in the 1960s to examine risk factors involved in pre-term birth and intrauterine growth retardation, and the consequences of these early adverse outcomes on subsequent morbidity. NFBC represents the world’s largest collection of data from early pregnancy until adult senescence, including almost every aspect of basic, epidemiologic and clinical data. NFBC was one of the first studies to confirm the harmful effects of maternal smoking on growth of fetus and child disability. The early-life data provides an invaluable reservoir to test prospective hypotheses linking early life exposure and later health. The NFBC data has contributed to research regarding epidemiology of psychiatric disorders, overweight, diabetes etc. NFBC has established strong network consisting of the world’s leading epidemiologists, statisticians, geneticists, biochemists, physiologists, endocrinologists and clinicians.
NFBCs include two longitudinal and prospective birth cohorts of women and offspring collected at 20-year intervals from the same provinces of Oulu and Lapland (Figure 1):
Figure 1. Flowchart of the two longitudinal data collections at different time points.
More information available from http://www.oulu.fi/nfbc/
Viimeksi päivitetty: 31.8.2016