Research Group of Oral Development and Orthodontics

General goals:

  • The relationships between facial morphology, genetic background factors, and general health in Northern Finland Birth Cohort 1966 (
  •  The effect of genetic and environmental background factors on tooth morphology occlusion and the development of malocclusions and craniofacial aberrations.
  • Normal and abnormal development of dentition and occlusion.
  • The effect of early treatment on population and individual level, and their effect on Quality of Life issues and the effect on the prevalence of malocclusions in the adulthood.

Used materials and methods

In the study of Northern Finland Birth Cohort 1966 the material comprises the oral examination material, 3D scans, facial photos and the genetic and the general medical and other background data.

The clinical research that is based on patient data is done mainly in collaboration with Oulu University Hospital and Oulu City Health Service.

In the KVANTTI research project the material comprises sex chromosome anomaly patient data and documents, including dental casts and x-rays, the measurements being done in comparison with control population.

In a Birth Cohort of Small Children the effect of environmental factors are examined on the formation of the head shape and occlusion. This is a study that is done in collaboration with Oulu University Hospital and uses 3D cameras (3DMd).

In the research of cleft lip- and palate patients, the characteristics of cleft patients and their parents are examined in relation to the genetic data, using x-ray images, clinical examinations, and genome studies.

In the research of early treatment, early orthodontic treatment is examined in clinical cohort or randomized studies, where the varying factor is the initiation age of the orthodontic treatment.

The study on orthognathic treatment is done as a prospective cohort study, where the quality of life issues and the occlusal problems are examined using clinical studies structured questionnaires.

The use of CBCT diagnostics is examined in a study where especially early diagnostics of problematically erupting cuspid is monitored.

The growth of TMJ and the factors in TMD are examined experimentally in a study the factor is the diet. The examination of TMJ is done by using modern 3D imaging methods and immunohistochemistry.


The research in the group is done in associated with the Medical Research Center of Oulu:


Research Group:
Professori Pertti Pirttiniemi
Dosentti Tuomo Heikkinen
Dosentti Raija Lähdesmäki
Dosentti Virpi Harila
DDS, PhD Anna-Sofia Silvia
PhD students:
Mitsuko Nakayama
Georgios Kanavakis
Laura Krooks
Johanna Julku
Minna Tervonen
Matti Hannula
Sigurd Hadler-Olsen
Ville Vuollo
Päivi Arvonen
Tuula Savolainen
Anniina Launonen
Raija Pentinpuro
Mari Maikku

Last updated: 5.12.2017