Tetri Sami

Epidemiology of acute brain injury


Research unit: Clinical Neuroscience


Group leader

Professor Sami Tetri (MD, PhD)


What do we do

The first aim of the research is to clarify factors that affect outcome after acute brain injury. Secondly, effectiveness of current treatments are studied, and finally to develop new treatments and counseling to better the outcome of patients with brain injury.

It is essential to identify subgroups that are in higher risk of having brain trauma. Intervention can be used for these individuals. Treatments after brain injury are not standardized and specific treatments affecting the outcome remains unknown. The economic burden of patients with stroke and brain trauma is enormous.

We have four main study projects:

1. Population based cohort of patients with intracerebrall hemorrhage

2. Observational, longitudinal cohort study of brain trauma patients

3. A double-blind randomized trial to compare the efficacy of intermittent pneumatic compression (IPC) with and without early anticoagulant treatment for prevention of venous thromboembolism (VTE) in patients with acute primary intracerebral hemorrhage (ICH) including comparison of the American and European guideline recommendations.

4. Study on skull bone metabolism in patients with craniectomy and cranioplasty after severe brain injury


Our team

Post doc researchers

  • Puljula Jussi, MD, PhD
  • Saloheimo Pertti, MD, PhD
  • Vaaramo Kalle, MD, PhD

PhD students

  • Korhonen Tommi, Med. stud.
  • Lahti Anna-Maija, Med. stud.
  • Löppönen Pekka, MD
  • Qian Cheng, MD

Other group members

  • Hillbom Matti, Professor emeritus


Where are we headed

Future goals is to better the outcome of patients with brain injury by identifying subgroups that will benefit for selective treatments as well as develop new more effective treatment guidelines. Our long term aim is to produce knowledge that can help to prevent brain injury and to develop effective treatments after the injury.


Our main collaborators

Professor Kari Majamaa, Oulu University, Department of Neurology
Associate professor Seppo Juvela, Helsinki University, Department of Clinical Neuroscience
Associate professor Atte Meretoja, University on Melbourne, Department of Neurology
Professor Willy Serlo, Oulu University, Department of Pediatrics
Professor Petri Lehenkari, Oulu University, Department of Anatomy and Cell Biology


How to find us


Last updated: 9.7.2019