Mechanisms of Organogenesis

Project description

Strategic research project of the University of Oulu
Focus institute: Biocenter Oulu
Faculty: Faculty of Biochemistry and Molecular Medicine (FBMM)

The problem of how multipotent cells assemble in a spatially and temporally controlled manner to well organized three dimensional functional structures during organogenesis is a major challenge. The process is directed by cell-cell and tissue interactions mediated by the associated signals exchanged by the cells. The fine details how this leads to well orchestrated anatomical structures is a challenge in all biological systems. The capacity to edit the genome also in human cells has set the stage to reveal the mechanistic details. Our project targets the fundaments of normal and the deregulated organ assembly programs. The project is part of the Finnish Centre of Excellence Programme funded by the Academy of Finland (Centre of Excellence Grant 2012 - 2017, 251314)

People

Seppo Vainio

Seppo Vainio

Research Unit leader
Susanna Kaisto

Susanna Kaisto

PhD Student