Lassi Rieppo

Lassi Rieppo


Postdoctoral researcher

38 peer reviewed publications in international journals. The publications have been cited 404 times, of which the most cited publication accounts for 65 citations. The author has a h-index of 11.00. (Scopus)


Dr. Rieppo acts as a postdoctoral researcher at the Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, Finland. Dr. Rieppo received funding for his postdoctoral project (Quantum cascade laser infrared spectroscopic tool for assessment of the quality of articular cartilage) from Academy of Finland for 2017-2020. His research has focused on characterization of osteoarthritic changes in cartilage and bone tissues using microscopic techniques. Particularly, he has utilized infrared microspectroscopy to analyze tissue composition. Dr. Rieppo has also founded his own research group recently. His new research topics include spectral histopathology of skin cancers and spectroscopic research of blood coagulation cascade. In these projects, machine learning algorithms are applied to infrared and Raman spectroscopic data to extract biochemical information from tissues and biofluids.

Research interests

  • infrared spectroscopy
  • raman spectroscopy
  • musculoskeletal diseases
  • skin cancers
  • machine learning

Social media

Selected publications

  • Rieppo, Lassi; Töyräs, Juha; Saarakkala, Simo (2017) Vibrational spectroscopy of articular cartilage. - Applied Spectroscopy Reviews 52 (3), 249-266 . [Original] [Self-archived]
  • Sarin, Jaakko K.; Rieppo, Lassi; Brommer, Harold; Afara, Isaac O.; Saarakkala, Simo; Töyräs, Juha (2017) Combination of optical coherence tomography and near infrared spectroscopy enhances determination of articular cartilage composition and structure. - Scientific Reports 7, 10586 .
  • Oinas, J.; Rieppo, L.; Finnilä, M. A. J.; Valkealahti, M.; Lehenkari, P.; Saarakkala, S. (2016) Imaging of Osteoarthritic Human Articular Cartilage using Fourier Transform Infrared Microspectroscopy Combined with Multivariate and Univariate Analysis. - Scientific Reports 6, 30008 . [Original] [Self-archived]
  • Rieppo, Lassi; Kokkonen, Harri T.; Kulmala, Katariina A. M.; Kovanen, Vuokko; Lammi, Mikko J.; Töyräs, Juha; Saarakkala, Simo (2017) Infrared microspectroscopic determination of collagen cross-links in articular cartilage. - Journal of biomedical optics 22 (3), 035007 . [Original] [Self-archived]
  • Rieppo L; Saarakkala S; Närhi T; Helminen HJ; Jurvelin JS; Rieppo J (2012) Application of second derivative spectroscopy for increasing molecular specificity of fourier transform infrared spectroscopic imaging of articular cartilage. - Osteoarthritis and Cartilage 20 (5), 451-459 . [Original]
  • Kobrina, Y.; Rieppo, L.; Saarakkala, Simo; Pulkkinen, H.J.; Tiitu, V.; Valonen, P.; Kiviranta, I.; Jurvelin, J.S.; Isaksson, H. (2013) Cluster analysis of infrared spectra can differentiate intact and repaired articular cartilage. - Osteoarthritis and Cartilage 21, 462-469 . [Original]

Thesis supervisions

Vesa Virtanen (PhD ongoing)
  • Detection of articular cartilage degeneration using infrared spectroscopy

  • PhD thesis ongoing

Mithilesh Prakash (PhD ongoing)
  • Optimization of multivariate regression techniques for near infrared spectroscopic characterization of articular cartilage

  • PhD thesis ongoing

Bijay Ratna Shakya (PhD ongoing)
  • Detection and grading of skin cancers using FTIR and Raman spectroscopy

  • PhD thesis ongoing