Sini Skarp

MSc

PhD Student
Genetics of musculoskeletal diseases

9 peer reviewed publications in international journals. The publications have been cited 31 times, of which the most cited publication accounts for 6 citations. The author has a h-index of 4.00. (Google Scholar)

Biography

Sini Skarp is a Ph.D. student studying the genetics of musculoskeletal diseases. The main focus of her research is investigating the rare genetic variation predisposing to musculoskeletal diseases using whole exome sequencing and in vitro studies. She also has experience of genome-wide association studies and cDNA microarray data analysis.

Research interests

  • Genetics of common diseases
  • Next generation sequencing
  • Musculoskeletal diseases

Social media

Selected publications

  • Skarp, Sini; Kämäräinen, Olli-Pekka; Wei, Gong-Hong; Jakkula, Eveliina; Kiviranta, Ilkka; Kröger, Heikki; Auvinen, Juha; Lehenkari, Petri; Ala-Kokko, Leena; Männikkö, Minna (2018) Whole exome sequencing in Finnish families identifies new candidate genes for osteoarthritis. - PLoS One 13 (8), e0203313 . [Original] [Self-archived]
  • Kraatari, Minna; Skarp, Sini; Niinimäki, Jaakko; Karppinen, Jaro; Männikkö, Minna (2017) A Whole Exome Study Identifies Novel Candidate Genes for Vertebral Bone Marrow Signal Changes (Modic Changes). - Spine 42 (16), 1201–1206 . [Original] [Self-archived]
  • Sliz, Eeva; Taipale, Mari; Welling, Maiju; Skarp, Sini; Alaraudanjoki, Viivi; Ignatius, Jaakko; Ruddock, Lloyd; Nissi, Ritva; Männikkö, Minna (2017) TUFT1, a novel candidate gene for metatarsophalangeal osteoarthritis, plays a role in chondrogenesis on a calcium-related pathway. - PLoS One 12 (4), e0175474 . [Original] [Self-archived]
  • Costantini, Alice; Skarp, Sini; Kampe, Anders; Mäkitie, Riikka E.; Pettersson, Maria; Männikkö, Minna; Jiao, Hong; Taylan, Fulya; Lindstrand, Anna; Mäkitie, Outi (2018) Rare Copy Number Variants in Array-Based Comparative Genomic Hybridization in Early-Onset Skeletal Fragility. - Frontiers in Endocrinology 9, 380 . [Original]