I have done throughout my career protein structure-function research. I am pioneers of protein crystallography in Finland and fetched expertise in the field at the time when this research could not yet be practiced in Finland. I was founding structural studies of proteins, first at the University of Turku and from 1997 at the University of Oulu, and I was the coordinator of the national structural biology research programme 2000-2002. My research interests have been enzymes related to both biotechnological applications and human physiology and diseases, most notably lignin peroxidase, the multifunctional enzyme MFE-2, which functions in fatty acid metabolism, and glycosyltransferases involved in the synthesis of glycans (sugar chains) involved in e.g. identification function on cell surface.
- Protein research
Eidgenössische Technische Hochschule Zürich, Sveitsi
European Molecular Biology Laboratory, Hamburg Outstation, Saksa