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Kalervo Hiltunen, M.D., Ph.D.

Peroxisomes and Mitochondria in Lipid Metabolism of Cells
 

Project leader: Prof. Kalervo Hiltunen, M.D., Ph.D.
Department of Biochemistry, Faculty of Science, University of Oulu

mailing address:
P.O.Box 3000, FIN-90014 University of Oulu, Finland

street address:
Linnanmaa Campus, University of Oulu, FIN-90570 Oulu, Finland
Phone: +358-(0)294 481150,
Fax: +358-8-553 1141;
e-mail: kalervo.hiltunen (at) oulu.fi

For more information, see Kalervo Hiltunen's home page. 

 

About the project

The proposed work is basic research in lipid biology and biochemistry with a tight link to biomedical topics of broad interest. Our research in lipid biology and biochemistry is focused on three interlinked topics:

  1. What links mitochondrial fatty acid synthesis (mtFAS), RNA processing, mitochondrial gene expression and mitochondrial respiration?
  2. What is the functional role of peroxisomal membrane protein 22 (Pxmp2)?
  3. How does break-down of fatty acids and modified fatty acid derivatives interact with the cellular regulatory network?

The subprojects require a deep understanding of lipid and protein biochemistry, and they address the regulatory interplay between cells and intracellular organelles and metabolic compartmentalization in a physiological context. Different model organisms (yeasts, mice, rats and humans) and technical approaches (e.g. protein chemistry, molecular genetics, molecular biology, membrane electrophysiology and structural biology) will be used to address particular biological questions.
 

Project details
 

  1. Background and Significance
  2. Recent Progress
  3. Future Goals
  4. Publications 2012-
  5. Doctoral Theses 2012
  6. Research Group Members
  7. National and International Activities
Last updated: 4.7.2013
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