Protein crystallography

Biocenter Oulu offers services (contact persons) related to its expertise in protein crystallographic structure determination and provide support for researchers not familiar with structural studies to get the structure determination process started.

We can offer the following services:

  • Characterization of proteins
     o Determination of molecular size with SLS instrument
     o Optimization of buffer content with DLS instrument
     o Study of protein stability with DSF instrument
  • Enzymology and ligand screening
     o Guiding and consultation of instrument usage

Protein sample

Characterization

Crystallization

Crystal quality check

Data collection

Structure determination

Structure analysis

Structure deposition

Events:

Contact persons:

Responsible scientists for the core facility:

Dr Lari Lehtiö
tel. +358-(0)294 481169 (office F126A)
e-mail: lari.lehtio (at) oulu.fi

Professor emeritus Rik Wierenga
tel. +358-(0)294 481199 (office F202B)
e-mail: rik.wierenga (at) oulu.fi

Postdoctoral scientist Tiila Kiema (data collection)
tel. +358-(0)294 481174 (office F217)
e-mail: tiila.kiema (at) oulu.fi

Postdoctoral scientist Kristian Koski
(remote data collection, courses, DLS, SLS, protein purification)
tel. +358-(0)294 481182 (office F216A)
e-mail: kristian.koski (at) oulu.fi

Project manager Outi Lampela
tel. +358-(0)294 486118 (office F005)
e-mail: outi.lampela (at) oulu.fi

Technical staff:

Ville Ratas (crystallization)
tel. +358-(0)294 481174 (office F216A)
e-mail: ville.ratas (at) oulu.fi

Ed Daniel (computing, IceBear)
tel. +358-(0)294 481151 (office F126B)
e-mail: edward.daniel (at) oulu.fi

 

Last updated: 15.11.2018