Puistola - publications and supervised doctoral dissertations

Selected publications:

  1. Sova H, Puistola U, Morin-Papunen L, Karihtala P. Metformin decreases serum 8-hydroxy-2'-deoxyguanosine levels in polycystic ovary syndrome. Fertil Steril. 2013 Feb;99(2):593-8. doi: 10.1016/j.fertnstert.2012.10.013. Epub 2012 Oct 31. PubMed PMID: 23122829.
  2. Sova H, Kangas J, Puistola U, Santala M, Liakka A, Karihtala P. Down-regulation of 8-hydroxydeoxyguanosine and peroxiredoxin II in the pathogenesis of endometriosis-associated ovarian cancer. Anticancer Res. 2012 Aug;32(8):3037-44. PubMed PMID: 22843871.
  3. Perren TJ, Swart AM, Pfisterer J, Ledermann JA, Pujade-Lauraine E, Kristensen G, Carey MS, Beale P, Cervantes A, Kurzeder C, du Bois A, Sehouli J, Kimmig R, Stähle A, Collinson F, Essapen S, Gourley C, Lortholary A, Selle F, Mirza MR, Leminen A, Plante M, Stark D, Qian W, Parmar MK, Oza AM; ICON7 Investigators. A phase 3 trial of bevacizumab in ovarian cancer. N Engl J Med. 2011 Dec 29;365(26):2484-96. doi: 10.1056/NEJMoa1103799. Erratum in: N Engl J Med. 2012 Jan 19;366(3):284. PubMed PMID: 22204725.
  4. Karihtala P, Kauppila S, Puistola U, Jukkola-Vuorinen A. Absence of the DNA repair enzyme human 8-oxoguanine glycosylase is associated with an aggressive breast cancer phenotype. Br J Cancer. 2012 Jan 17;106(2):344-7. doi: 10.1038/bjc.2011.518. Epub 2011 Nov 22. PubMed PMID: 22108520; PubMed Central PMCID: PMC3261678.
  5. Vuorela M, Pylkäs K, Hartikainen JM, Sundfeldt K, Lindblom A, von Wachenfeldt Wäppling A, Haanpää M, Puistola U, Rosengren A, Anttila M, Kosma VM, Mannermaa A, Winqvist R. Further evidence for the contribution of the RAD51C gene in hereditary breast and ovarian cancer susceptibility. Breast Cancer Res Treat. 2011 Dec;130(3):1003-10. doi: 10.1007/s10549-011-1677-x. Epub 2011 Jul 13. PubMed PMID: 21750962.
  6. Laatio L, Myllynen P, Serpi R, Rysä J, Ilves M, Lappi-Blanco E, Ruskoaho H, Vähäkangas K, Puistola U. BMP-4 expression has prognostic significance in advanced serous ovarian carcinoma and is affected by cisplatin in OVCAR-3 cells. Tumour Biol. 2011 Oct;32(5):985-95. doi: 10.1007/s13277-011-0200-7. Epub 2011 Jun 15. PubMed PMID: 21674241.
  7. Karihtala P, Kauppila S, Puistola U, Jukkola-Vuorinen A. Divergent behaviour of oxidative stress markers 8-hydroxydeoxyguanosine (8-OHdG) and 4-hydroxy-2-nonenal (HNE) in breast carcinogenesis. Histopathology. 2011 May;58(6):854-62. doi: 10.1111/j.1365-2559.2011.03835.x. PubMed PMID: 21585424.
  8. Pylväs M, Puistola U, Laatio L, Kauppila S, Karihtala P. Elevated serum 8-OHdG is associated with poor prognosis in epithelial ovarian cancer. Anticancer Res. 2011 Apr;31(4):1411-5. PubMed PMID: 21508394.
  9. Sova H, Morin-Papunen L, Puistola U, Karihtala P. Distinctively low levels of serum 8-hydroxydeoxyguanosine in women with polycystic ovary syndrome. Fertil Steril. 2010 Dec;94(7):2670-3. doi: 10.1016/j.fertnstert.2010.03.049. Epub 2010 Apr 28. PubMed PMID: 20430377.
  10. Karihtala P, Mäenpää J, Turpeenniemi-Hujanen T, Puistola U. Front-line bevacizumab in serous epithelial ovarian cancer: biomarker analysis of the FINAVAST trial. Anticancer Res. 2010 Mar;30(3):1001-6. PubMed PMID: 20393027.
  11. Pylväs M, Puistola U, Kauppila S, Soini Y, Karihtala P. Oxidative stress-induced antioxidant enzyme expression is an early phenomenon in ovarian carcinogenesis. Eur J Cancer. 2010 Jun;46(9):1661-7. doi: 10.1016/j.ejca.2010.02.006. Epub 2010 Mar 4. PubMed PMID: 20206498.
  12. Sova H, Jukkola-Vuorinen A, Puistola U, Kauppila S, Karihtala P. 8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer. Br J Cancer. 2010 Mar 16;102(6):1018-23. doi: 10.1038/sj.bjc.6605565. Epub 2010 Feb 23. PubMed PMID: 20179711; PubMed Central PMCID: PMC2844025.
  13. Kellokumpu-Lehtinen PL, Puistola U, Paija O, Taimela E, Hirvonen O, Raassina S, Riska H. Anaemia: a rare but neglected problem among Finnish patients receiving chemotherapy for solid tumours. Support Care Cancer. 2011 Jan;19(1):149-53. doi: 10.1007/s00520-009-0809-x. Epub 2010 Jan 26. PubMed PMID: 20101415.
  14. Karihtala P, Soini Y, Vaskivuo L, Bloigu R, Puistola U. DNA adduct 8-hydroxydeoxyguanosine, a novel putative marker of prognostic significance in ovarian carcinoma. Int J Gynecol Cancer. 2009 Aug;19(6):1047-51. doi: 10.1111/IGC.0b013e3181ad0f0d. PubMed PMID: 19820366.
  15. Kumpulainen S, Sankila R, Leminen A, Kuoppala T, Komulainen M, Puistola U, Hurme S, Hiekkanen H, Mäkinen J, Grénman S. The effect of hospital operative volume, residual tumor and first-line chemotherapy on survival of ovarian cancer - a prospective nation-wide study in Finland. Gynecol Oncol. 2009 Nov;115(2):199-203. doi: 10.1016/j.ygyno.2009.07.011. Epub 2009 Aug 19. PubMed PMID: 19695688.
  16. Kenemans P, Bundred NJ, Foidart JM, Kubista E, von Schoultz B, Sismondi P, Vassilopoulou-Sellin R, Yip CH, Egberts J, Mol-Arts M, Mulder R, van Os S, Beckmann MW; LIBERATE Study Group. Safety and efficacy of tibolone in breast-cancer patients with vasomotor symptoms: a double-blind, randomised, non-inferiority trial. Lancet Oncol. 2009 Feb;10(2):135-46. doi: 10.1016/S1470-2045(08)70341-3. Epub 2009 Jan 23. PubMed PMID: 19167925. 
  17. Kuoppala T, Mäenpää J, Tomas E, Puistola U, Salmi T, Grenman S, Lehtovirta P,Fors M, Luukkaala T, Sipilä P. Surgically staged high-risk endometrial cancer:randomized study of adjuvant radiotherapy alone vs. sequentialchemo-radiotherapy. Gynecol Oncol. 2008 Aug;110(2):190-5. doi:10.1016/j.ygyno.2008.03.020. Epub 2008 Jun 4. PubMed PMID: 18534669. 
  18. Hynninen P, Vaskivuo L, Saarnio J, Haapasalo H, Kivelä J, Pastoreková S,Pastorek J, Waheed A, Sly WS, Puistola U, Parkkila S. Expression of transmembrane carbonic anhydrases IX and XII in ovarian tumours. Histopathology. 2006Dec;49(6):594-602. PubMed PMID: 17163844.
  19. Launonen V, Stenbäck F, Puistola U, Bloigu R, Huusko P, Kytölä S, Kauppila A,Winqvist R. Chromosome 11q22.3-q25 LOH in ovarian cancer: association with a more aggressive disease course and involved subregions. Gynecol Oncol. 1998 Nov;71(2):299-304. PubMed PMID: 9826475.
  20. Huusko P, Pääkkönen K, Launonen V, Pöyhönen M, Blanco G, Kauppila A, Puistola U, Kiviniemi H, Kujala M, Leisti J, Winqvist R. Evidence of founder mutations in  Finnish BRCA1 and BRCA2 families. Am J Hum Genet. 1998 Jun;62(6):1544-8. PubMed PMID: 9585608; PubMed Central PMCID: PMC1377159.   

Supervised doctoral dissertations:

  • Anna Westerlund
  • Marita Rauvala
  • Liisa Laatio
  • Henri Sova 

Last updated: 13.11.2018