Joonas H Kauppila, Assistant Professor of Surgery, received his M.D. in 2013 and Ph.D. in 2014 from the University of Oulu, Finland. He became a Docent in Cancer Biology in 2015, at the age of 27 years, as one of the youngest docents in medical sciences ever in Finland. Kauppila worked as a Research Fellow at Karolinska Insitutet, Sweden from 2016 until 2019.
He is leading his independent research team since 2019, and is currently pursuing a specialist degree in Gastrointestinal Surgery. His key interest areas are upper gastrointestinal disorders.
- Esophageal cancer
- Gastric cancer
- Gastroesophageal reflux disease
- Bariatric surgery
- Cancer immunology
- Cancer biomarkers
Description of Research
Dr Kauppila's research is mainly focused on reducing the burden of upper gastrointestinal diseases. More specifically his aims are to improve the treatment, survival and survivorship of patients with esophagogastric cancer, and patients undergoing antireflux or bariatric surgery. These are achieved by combining epidemiological, clinical and molecular biology methods in his research projects.
Kauppila actively collaborates with surgery and pathology groups in all medical universities in Finland in the FINEGO-study. Active international collaborations include the groups of Jesper Lagergren, Pernilla Lagergren and Magnus Nilsson at Karolinska Institutet, Prof Lynge group at University of Copenhagen, Denmark, Assoc. Prof Ness-Jensen group at NTNU, Norway, Tryggvadóttir group at University of Reykjavik, Iceland and Mr Sheraz Markar at Imperial College London, UK. Other international collaborations include the Oesophago-Gastric Anastomosis Audit (OGAA), as well as CovidSurg and CovidSurg-Cancer studies.
His research has been funded by the Sigrid Juselius Foundation, The Finnish Cancer Society, Orion Research Foundation, Päivikki and Sakari Sohlberg Foundation, Mary and Georg C. Ehrnroot Foundation, as well as Thelma Mäkikyrö Foundation.
Ten Key Publications
Kauppila JH; Santoni G; Tao W; Lynge E; Jokinen J; Tryggvadóttir L; Ness-Jensen E; Pukkala E; von Euler-Chelpin M; Lagergren J. (2020)
Risk factors for suicide after bariatric surgery in a population-based nationwide study in five Nordic countries.
Annals of Surgery. Accepted Manuscript. IF 9.2
Kauppila JH; Santoni G; Tao W; Lynge E; Koivukangas V; Tryggvadóttir L; Ness-Jensen E; Romundstad P; Pukkala E; von Euler-Chelpin M; Lagergren J. (2020)
Reintervention or mortality within 90 days of bariatric surgery: population-based cohort study.
British Journal of Surgery. In press. IF 5.6
Kauppila, JH; Johar, A; Lagergren, P. (2020)
Postoperative Complications and Health-related Quality of Life 10 Years After Esophageal Cancer Surgery.
Annals of Surgery 271 (2), 311-316. IF 9.2
Kauppila, JH; Johar, A; Lagergren, P. (2020)
Medical and Surgical Complications and Health-related Quality of Life After Esophageal Cancer Surgery.
Annals of Surgery 271 (3), 502-508. IF 9.2
Kauppila, JH; Ohtonen, P; Karttunen, TJ; Kokkola, A; Laine, S; Rantanen, T; Ristimäki, A; Räsänen, JV; Saarnio, J; Sihvo, E; Toikkanen, V; Tyrväinen, T. (2019)
Finnish National Esophago-Gastric Cancer Cohort (FINEGO) for studying outcomes after oesophageal and gastric cancer surgery: A protocol for a retrospective, population-based, nationwide cohort study in Finland.
BMJ Open 9 (1), e024094. IF 2.4.
Kauppila, JH; Tao, W; Santoni, G; von Euler-Chelpin, M; Lynge, E; Tryggvadottir, L; Ness-Jensen, E; Romundstad, P; Pukkala, E; Lagergren, J. (2019)
Effects of Obesity Surgery on Overall and Disease-Specific Mortality in a 5-Country Population-Based Study.
Gastroenterology 157 (1), 119-127. IF 20.9
Gottlieb-Vedi, E; Kauppila, JH; Malietzis, G; Nilsson, M; Markar, SR; Lagergren, J. (2019)
Long-term Survival in Esophageal Cancer After Minimally Invasive Compared to Open Esophagectomy: A Systematic Review and Meta-analysis.
Annals of Surgery 270 (6), 1005-1017. IF 9.2
Kemi, N; Eskuri, M; Ikäläinen, J; Karttunen, TJ; Kauppila, JH (2019)
Tumor Budding and Prognosis in Gastric Adenocarcinoma.
American Journal of Surgical Pathology 43 (2), 229-234. IF 6.2
Kemi, N; Eskuri, M; Herva, A; Leppänen, J; Huhta, H; Helminen, O; Saarnio, J; Karttunen, TJ; Kauppila, JH. (2018)
Tumour-stroma ratio and prognosis in gastric adenocarcinoma.
British Journal of Cancer 119 (4), 435-439. IF 5.4
Kauppila, JH; Xie, S; Johar, A; Markar, SR; Lagergren, P. (2017)
Meta-analysis of health-related quality of life after minimally invasive versus open oesophagectomy for oesophageal cancer.
British Journal of Surgery 104 (9), 1131-1140. IF 5.6