Karl-Heinz Herzig

Karl-Heinz Herzig


Physiology and Internal Medicine

395 peer reviewed publications in international journals. The publications have been cited 8580 times, of which the most cited publication accounts for 638 citations. The author has a h-index of 46.00. (web of science)


Many diseases are related to unequal input/output balance, imbalance/lack of macronutrients, toxic compounds or physical inactivity. The different organs involved in keeping homeostasis (brain-gut/microbiome-fat-liver-muscle) are tightly communicating with each other via peptides, proteins, nutrients and nerves (adipokines, hepatokines, myokines, gut peptides, neurotransmitters). Understanding the communication of this organ cross talk might decipher the molecular mechanisms in the pathogenesis of metabolic diseases like diabetes and obesity/metabolic syndrome. Furthermore, the increased energy storages lead to inflammation affecting the signaling cascades. Our mission is to elucidate the communication signals and pathways which might lead to novel therapeutic targets and new strategies for the prevention of these diseases.

Research interests

  • Cross organ communication
  • Metabolic syndrome
  • Nutrition and Exercise
  • Intestine and Microbiome
  • Cancer

Scientific merits

Professional and community activities

  • Scientific board of the International Society for BioActive Peptides
  • Editor for Metabolism in Acta Physiologica
  • Editor in Chief - Peptides
  • Board Member in the Council of the Scandinavian Physiological Society (SPS) 2008-2016
  • Referee for international research evaluations (FWO, NSF, NSC, NFS, DFG, EU)

Research groups

  • Molecular Physiology

Thesis supervisions

Supervised 19 PhD or MD-PhD thesis to completion