Salla Ruskamo

Salla Ruskamo


Postdoctoral Researcher
Biochemistry and structural biology

20 peer reviewed publications in international journals. The publications have been cited 265 times, of which the most cited publication accounts for 72 citations. The author has a h-index of 9.00. (Web of Science)


I did my PhD at the University of Jyväskylä (2007-2011) in the group of Prof. Jari Ylänne, focusing on the structural studies of the actin-binding protein filamin. In 2011, I joined the group of Prof. Petri Kursula at the University of Oulu and started to work with myelin-specific proteins. In 2014-2018, I worked as a postdoctoral researcher of the Academy of Finland and investigated the structure and organization of myelin-specific integral membrane proteins. Recently, we got interested in the molecular pathomechanisms of myelin-related disorders such as Charcot-Marie-Tooth neuropathy and multiple sclerosis.

Research interests

  • Structure and function of myelin-specific membrane proteins
  • Molecular mechanisms of myelin-related disorders
  • Protein-lipid interactions
  • Integral membrane proteins


Research groups

  • Postdoctoral researcher, Structural biology of myelin sheath

Selected publications

  • Ponna, Srinivas Kumar; Ruskamo, Salla; Myllykoski, Matti; Keller, Corinna; Boeckers, Tobias M.; Kursula, Petri (2018) Structural basis for PDZ domain interactions in the post-synaptic density scaffolding protein Shank3. - Journal of Neurochemistry 145 (6), 449-463 . [Original]
  • Laulumaa, Saara; Nieminen, Tuomo; Raasakka, Arne; Krokengen, Oda C.; Safaryan, Anushik; Hallin, Erik I.; Brysbaert, Guillaume; Lensink, Marc F.; Ruskamo, Salla; Vattulainen, Ilpo; Kursula, Petri (2018) Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the beta barrel in fatty acid binding proteins. - Bmc structural biology 18, 8 . [Original]
  • Ruskamo, Salla; Nieminen, Tuomo; Kristiansen, Cecilie K.; Vatne, Guro H.; Baumann, Anne; Hallin, Erik I.; Raasakka, Arne; Joensuu, Päivi; Bergmann, Ulrich; Vattulainen, Ilpo; Kursula, Petri (2017) Molecular mechanisms of Charcot-Marie-Tooth neuropathy linked to mutations in human myelin protein P2. - Scientific Reports 7, 6510 . [Original] [Self-archived]
  • Raasakka, Arne; Ruskamo, Salla; Kowal, Julia; Barker, Robert; Baumann, Anne; Martel, Anne; Tuusa, Jussi; Myllykoski, Matti; Buerck, Jochen; Ulrich, Anne S.; Stahlberg, Henning; Kursula, Petri (2017) Membrane Association Landscape of Myelin Basic Protein Portrays Formation of the Myelin Major Dense Line. - Scientific Reports 7, 4974 . [Original] [Self-archived]
  • Tuusa, Jussi; Raasakka, Arne; Ruskamo, Salla; Kursula, Petri (2017) Myelin-derived and putative molecular mimic peptides share structural properties in aqueous and membrane-like environments. - Multiple sclerosis and demyelinating disorders 2, 4 . [Original]
  • Kaur, Inderjeet; Ruskamo, Salla; Koivunen, Jarkko; Heljasvaara, Ritva; Lackman, Jarkko J.; Izzi, Valerio; Petäjä-Repo, Ulla E.; Kursula, Petri; Pihlajaniemi, Taina (2018) The N-terminal domain of unknown function (DUF959) in collagen XVIII is intrinsically disordered and highly O-glycosylated. - Biochemical journal 475 (22), 3577-3593 . [Original] [Self-archived]

Research visits

  • University of Bergen, Norway

  • C-CINA, University of Basel, Switzerland

  • University of Yale, New Haven, USA