Breast Cancer Genetics Research Group
Research group information
Research group leader
Research group description
The focus of our Breast Cancer Genetics team is on resolving the molecular genetics and biology behind the inherited breast cancer predisposition. For this we use breast cancer case cohorts collected from Northern Finnish population with homogenous genetic background and implement several high-throughput genomic methods for their comprehensive genetic analysis. The effects of the breast cancer predisposing variants are investigated with functional genomics, biochemical and tumor modelling approaches, which can provide important insights into the tumorigenesis mechanisms and may lead to implementation of more effective diagnostic and prognostic tools, as well as targeted treatment.
Where are we headed
We anticipate that this project combining the expertise in molecular and clinical genetics, biochemical investigations, and tumor modelling together with the dedicated collaborators will refine the clinical risk assessment of high-risk individuals, increase the understanding of the cellular mechanisms behind breast cancer development and ultimately promote the development of more targeted cancer therapies.
Our main collaborators
- Clinicians and clinical researchers at Oulu University Hospital
- Clinical laboratory geneticists at Nordlab Oulu
- Breast cancer Association Consortium
- PALB2 interest group
How to find us
Research Unit of Translational Medicine, Medical Faculty