Oral cancer research group

Research group information

Contact information

Research group leader

Research group description

Oral tongue squamous cell carcinoma (OTSCC) is a very aggressive cancer with poor survival (50%). Our research focuses on identification of prognostic markers for improved diagnostics and to understand the role of the tumor microenvironment in cancer development. In addition, we have developed a human uterus leiomyoma tissue-based Myoma discs and Myogel extracellular matrix, which are providing a more accurate environment for human cancer cell testing. Based on Myogel we are developing a reliable ex vivo method enabling “personalized medicine “treatment approach.

Our team

Where are we headed

  • Identify novel prognostic markers for OTSCC diagnostics

  • Resolve molecular mechanisms in the oral cancer tumor microenvironment for future diagnostics and therapeutics

  • Develop the Myogel for in vitro cancer cell analyses

  • Develop an ex vivo personalized medicine method for OTSCC

Our main collaborators

  • Professor Ricardo Coletta, Piracicaba Dental School, State University of Campinas, Brazil

  • Professor Antti Mäkitie and professor Peeter Karihtala University of Helsinki

  • Docent Petri Koivunen, Oulu University Hospital

  • Professor Ilmo Leivo and professor Reidar Grenman, University of Turku

  • Professor Veli-Matti Kosma and professor Ylermi Soini, University of Eastern Finland

  • Professor Marilena Vered, The Chaim Sheba Medical Center, Tel Aviv University, Israel

  • Associate professors Gunbjørg Svineng and Elin Hadler-Olsen, UiT The Arctic University of Norway, Norway

  • Professor Sara Zanivan, CRUK Beatson Institute and Institute of Cancer Sciences, University of Glasgow, UK

  • Docent Anniina Färkkilä, University of Helsinki

How to find us

Research Unit of Translational Medicine, Faculty of Medicine, University of Oulu

tuula.salo[at]oulu.fi, Tel. 040 5441560