Fast, sensitive and portable NMR methods for characterizing porous structures, fluid dynamics and molecular exchange phenomena in biomaterials

Thesis event information

Date and time of the thesis defence

Place of the thesis defence

L6, University of Oulu

Topic of the dissertation

Fast, sensitive and portable NMR methods for characterizing porous structures, fluid dynamics and molecular exchange phenomena in biomaterials

Doctoral candidate

Master of Science (MSc) Yashu Kharbanda

Faculty and unit

University of Oulu Graduate School, Faculty of Science, NMR Research Unit

Subject of study

Physics, NMR spectroscopy

Opponent

Associate professor Dr. Diana Bernin, Chalmers University of Technology

Custos

Professor Ville-Veikko Telkki, University of Oulu

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Biomaterial characterization by nuclear magnetic resonance spectroscopy

This study focuses on developing and applying one- and two-dimension Laplace NMR (LNMR) methods for biomaterials research. LNMR experiments are especially useful for biomaterials characterization because they are non-invasive, non-destructive, and give multiscale information about the pore sizes in the range of nanometers to millimeters. Especially, the thesis concentrates on determining pore sizes, fluid dynamics and molecular exchange phenomena in biomaterials. Two-dimensional Laplace NMR experiments are accelerated by spatial encoding, enabling single-scan measurements. The method is called ultrafast LNMR. It reduces the experiment time by one to three orders of magnitude. Furthermore, the single-scan approach significantly facilitates the use of nuclear spin hyperpolarization techniques to boost the sensitivity of experiments by several orders of magnitude.
Last updated: 21.11.2022