Many types of phantoms were developed to mimic tissue with relevant optical properties for biomedical optics applications. Materials currently used include Intralipid, polyacrylamide gels, albumin, fibrin, agar, epoxy resin and silicon filled up by micro- and nanoparticles. Usually, substances used nowadays absorb or evaporate water causing alterations in the phantom optical properties over time. Agar and albumin phantoms rapidly degrade due to fungal growth. To this end, phantoms insoluble in water with a long life span (months) are of high necessity.
We focus on manufacturing of fully functional capillary network embedded into the multilayer phantom. Additionally, a possibility to model a vascular pathology such as stenosis or aneurysm is taken into account.
Manufactured capillary system in a transparent phantom layer.
A.V. Bykov, A.P. Popov, A.V. Priezzhev, R. Myllylä, “Multilayer tissue phantoms with functioning capillary system for OCT and DOCT imaging”, Proc. SPIE 8091, 80911R (2011).
A.V. Bykov, A.P. Popov, M. Kinnunen, T. Prykäri, A.V. Priezzhev, R. Myllylä, “Skin phantoms with realistic vessel structure for OCT measurements”, Proc. SPIE 7376, 73760F (2010).