Khaled Abass

1. Abass K., Reponen P., Rautio A., Pelkonen O. Characterization of furathiocarb metabolism in in vitro human liver microsomes and recombinant cytochrome P450 enzymes. Toxicology Reports (2022). In press (IF:4.81)
2. Basu N., Abass K., Dietz R., Kruemmel E., Rautio A., Weihe P. The impact of mercury contamination on human health in the Arctic: A state of the science review. Science of The Total Environment (2022). In press (IF: 7.9).
3. Abass K., Reponen P., Rautio A., Pelkonen O. Metabolic profiling and in vitro-in vivo extrapolation of furathiocarb in mammalian hepatic microsomes. Toxicology Reports (2022). In press (IF:4.81).
4. Abass K., Unguryanu T, Junqué E., Mazej D., Tratnik JS, Horvat M., Grimalt JO, Myllynen P., Rautio A. Pilot study on the concentrations of organochlorine compounds in pregnant women and local food items from the Finnish Lapland. Environmental research, (2022), In press (IF: 5.02).
5. Sripada K., Wierzbicka A., Abass K., Grimalt J., Erbe A., Röllin H., Weihe P., Díaz G. J., Singh R., Visnes T., Rautio A., Odland J. Ø., Wagner M., A Children’s Health Perspective on Nano- and Microplastics. Environmental Health Perspectives, In press (IF: 8.38).
6. Palaniswamy S., Abass K., Rysä J., Odland J. Ø., Grimalt J. O., Rautio A., Järvelin M. R. Non-occupational exposure to pesticides and health markers in general population in Northern Finland: Differences between sexes. Environment international, (2021). 156, 106766. (IF: 9.6).
7. Xu, S., Hansen, S., Rautio, A., Järvelin, M. R., Abass, K., Rysä, J., Palaniswamy, S., Huber, S., Grimalt, J. O., Dumas, P., & Odland, J. Ø. Monitoring temporal trends of dioxins, organochlorine pesticides and chlorinated paraffins in pooled serum samples collected from Northern Norwegian women: The MISA cohort study. Environmental research, (2021), 111980. (IF: 5.02).
8. Abass K., Pelkonen O., Rautio A. Chloro-s-triazenes - toxicokinetic, toxicodynamic, human exposure, and regulatory considerations. Current Drug Metabolism, (2021), 22(8): 645 - 656 (IF: 3.7).
9. Larsen JN, Schweitzer P, Abass K, Doloisio N, Gartler S, Ingeman-Nielsen T, Ingimundarson JH, Jungsberg L, Meyer A, Rautio A, Scheer J, Timlin U, Vanderlinden J-P, Vullierme M. Thawing Permafrost in Arctic Coastal Communities: A Framework for Studying Risks from Climate Change. Sustainability. (2021); 13(5):2651. (IF: 3.3).
10. Küblbeck J, Vuorio T, Niskanen J, Fortino V, Braeuning A, Abass K, Rautio A, Hakkola J, Honkakoski P, Levonen AL. The EDCMET Project: Metabolic Effects of Endocrine Disruptors. Int J Mol Sci. (2020) Apr 24;21(8):3021. (IF: 4.6)
11. Palaniswamy S., Piltonen T., Koiranen M., Mazej D., Järvelin MR., Abass K., Rautio A., Sebert S., The association between blood copper concentration and biomarkers related to cardiovascular disease risk–analysis of 206 individuals in the Northern Finland Birth Cohort 1966. Journal of Trace Elements in Medicine and Biology, (2019) 51, 12-18. (IF: 3.8).
12. Abass A., Waits A., Emelyanova A., Miettinen I., Lavikainen A., Rautio A., Oksanen A., One Arctic- One Health project report. Finnish Food Authority Research Reports (2019). ISSN 2490-1180. ISBN 978-952-358-005-3 (pdf).
13. Abass A., Emelyanova A., Rautio A., Temporal trends of contaminants in Arctic human populations. Environmental Science and Pollution Research, (2018) 1-17. (IF: 3.0)
14. Waits A., Emelyanova A., Oksanen A., *Abass K., Rautio A., Human infectious diseases and the changing climate in the Arctic. Environment international (2018) 121, 703-713. (IF: 9.6)
15. Adlard B., Donaldson SG., Odland JO., Weihe P., Berner J., Carlsen A., Bonefeld-Jorgensen EC., Dudarev AA., Gibson JC., Krümmel EM., Olafsdottir K., Abass K., Rautio A., Bergdahl IA., Mulvad G. Future directions for monitoring and human health research for the Arctic Monitoring and Assessment Programme. Global Health Action (2018) 11, (1). (IF: 2.4)
16. Carlsson P., Breivik K., Brorström-Lundén E., Cousins I., Christensen J., Grimalt JO., Halsall C., Kallenborn R., Abass K., Lammel G., Munthe J., MacLeod M., Odland JØ., Pawlak J., Rautio A., Reiersen LO., Schlabach M., Stemmler I., Wilson S., Wöhrnschimmel H. Polychlorinated biphenyls (PCBs) as sentinels for the elucidation of Arctic environmental change processes: a comprehensive review combined with ArcRisk project results. Environmental Science and Pollution Research, (2018) 1-30. (IF: 3.0)
17. Abass K., Huusko A., Knutsen HK., Nieminen P., Myllynen P., Meltzer HM., Vahakangas A., Rautio A., Quantitative estimation of mercury intake by toxicokinetic modelling based on total mercury levels in humans, Environment International (2018), 114, 1-11. (IF: 9.6)
18. Abass K., Koiranen M., Mazej D., Snoj J., Tratnik J., Horvat M., Hakkola J., Järvelin MR., Rautio A., Arsenic, cadmium, lead and mercury levels in blood of Finnish adults and their relation to diet, lifestyle habits and sociodemographic variables. Environmental Science and Pollution Research, (2017) 24: 1347. (IF: 3.0)
19. Abass K., Carlsen A., Rautio A., New approaches in human health risk assessment. International Journal of Circumpolar Health, (2016), 75: 33845 (IF: 1.2)
20. Abass K., An investigation into the formation of tebufenozide’s toxic aromatic amine metabolites in human in vitro hepatic microsomes, Pesticides Biochemistry and Physiology, 1333, (2016) pp. 73-78. (IF: 3.9)
21. Elsebai M., Abass K., Hakkola J., Atawia A., Farag M., The wild Egyptian artichoke as a promising functional food for the treatment of hepatitis C virus as revealed via UPLC-MS and clinical trials. Food & Function, 13(7) (2016) pp. 3006-16. (IF: 5.3)
22. Pelkonen O., Pasanen M., Tolonen A., Koskinen M., Hakkola J., Abass K., Laine J., Hakkinen M., Juvonen R., Auriola S., Storvik M., Huuskonen P., Rousu T., Rahikkala M., Reactive metabolites in early drug development: predictive in vitro tools, Current Medicinal Chemistry. 22(4) (2015), pp. 538-550. (IF: 4.5)
23. Nieminen P., Abass K., Vähäkangas K., Rautio A., Statistical significance and number of outcome variables in environmental health studies., Biomedical and Environmental Sciences, 28 (9) (2015) pp. 666-673. (IF: 2.6)
24. Abass K., Reponen P., Mattila S., Rautio A., Pelkonen O. Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models. Toxicology Letters, 224 (2014), pp. 300-309. (IF:4.3)
25. Abass K., Reponen P., Mattila S., Rautio A., Pelkonen O. Comparative metabolism of benfuracarb in in vitro mammalian hepatic microsomes model and its implications for chemical risk assessment. Toxicology Letters, 224 (2014), pp. 290-299. (IF: 4.3)
26. Abass K., Huusko A., Nieminen P., Myllynen P., Pelkonen O., Vahakangas K., Rautio A. Estimation of health risk by using toxicokinetic modelling: A case study of polychlorinated biphenyl PCB153. Journal of Hazardous Materials. 261 (2013) 1-10. (IF: 10.5)
27. Abass K. From in vitro hepatic metabolic studies towards human health risk assessment: A case study of diuron and carbosulfan. Pesticides Biochemistry and Physiology, 107 (2013) 258–265. (IF: 3.9)
28. *Abass K., Pelkonen O. The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: Comparison of the N-in-one and single substrate approaches. Toxicology In vitro. 27 (2013) 1584-1588. (IF: 3.1)
29. Pelkonen O., Abass K., Wiesner J. Thujone and thujone-containing herbal medicinal and botanical products: Toxicological assessment. Regulatory Toxicology and Pharmacology. 65 (2013) 100–107. (IF: 3.2)
30. Pelkonen O., Turpeinen M., Hakkola J., Abass K., Pasanen M., Raunio H. How to preserve, induce or incorporate metabolism into the in vitro cellular system, Toxicology in vitro. 27 (2013) 1578–1583. (IF: 3.1)
31. Abass, K., Lämsä, V., Reponen, P., Küblbeck, J., Honkakoski, P., Mattila, S., Pelkonen, O., Hakkola, J. Characterization of human cytochrome P450 induction by pesticides, Toxicology. 294 (2012) 17-26. (IF: 4.2)
32. Abass K., Reponen P., Mattila S., Pelkonen O. Metabolism of α-thujone in human hepatic preparations in vitro. Xenobiotica. 14 (2011) 101-111. (IF: 1.9)
33. Sevior D., Hokkanen J., Tolonen A., Abass K., Tursas L., Pelkonen O., Ahokas J. Rapid screening of commercially available herbal products for the inhibition of major human hepatic cytochrome P450 enzymes using the N-in-one cocktail. Xenobiotica, 40 (2010) 245-254. (IF: 1.9)
34. Reponen P, Abass K., Sampo M, Pelkonen O. Overview of the metabolism and interactions of pesticides in hepatic in vitro systems. International Journal of Environmental Analytical Chemistry, 90 (2010) 429-437. (IF: 2.8)
35. Abass K., Reponen P., Sampo M., Pelkonen O. Metabolism of Carbosulfan II. Human interindividual variability in the in vitro hepatic biotransformation and the identification of cytochrome P450 isoforms involved. Chemico-Biological Interactions, 185 (2010) 163-173. (IF:5.1).
36. Abass K., Reponen P., Sampo M., Pelkonen O. Metabolism of carbosulfan. I. Species differences in the in vitro biotransformation by mammalian hepatic microsomes including human. Chemico-Biological Interactions. 181 (2009), 210-219. (IF:5.1)
37. Abass K., Turpeinen M., Pelkonen O. An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes. Journal of environmental Science and Health, Part B, 44 (2009) 553 – 563. (IF: 1.6)
38. Abass K., Reponen P., Turpeinen M., Jalonen J., Pelkonen O. Characterization of diuron N-demethylation by mammalian hepatic microsomes and cDNA-expressed human cytochrome P450 enzymes. Drug Metabolism and Disposition, 35 (2007) 1634-1641. (IF: 3.2)
39. Abass K., Reponen P., Jalonen J., Pelkonen O. In vitro metabolism and interaction of profenofos by human, mouse and rat liver preparations. Pesticides Biochemistry and Physiology, 87 (2007) 238–247. (IF: 3.9)
40. Abass K., Reponen P., Jalonen J., Pelkonen O. In vitro metabolism and interactions of the fungicide metalaxyl in human liver preparations. Environmental Toxicology and Pharmacology, 23 (2007) 39–47. (IF: 4.6)

Peer-reviewed book Sections and assessments

41. Abass K., Dudarev A., Khoury C., Human health risks associated with contaminants in the Arctic. In Arctic Monitoring and Assessment Programme AMAP 2021: Human Health in the Arctic. Oslo, Norway. In press
42. Adlard B, Bonefeld-Jorgensen EC, Dudarev A., Olafsdottir K., Byrne S., Berner J, Laird B, Ratelle M., Lemire M., Ayotte P, Long M., Toft G., Petersen MS, Weihe P., Berg V., Averina M, Wennberg M., Nordstrom K, Rautio A., Abass K. Levels and trends of contaminants in human. In Arctic Monitoring and Assessment Programme AMAP 2021: Human Health in the Arctic. Oslo, Norway. In press
43. Berner J., Rautio A., Abass K., Jore S. Arctic and global contexts In Arctic Monitoring and Assessment Programme AMAP 2021: Human Health in the Arctic. Oslo, Norway. In press
44. Weihe P., Basu N., Krummel E. Abass K., Rautio A., What is the Impact of Mercury Contamination on Human Health in the Arctic? 2021 Update. In Arctic Monitoring and Assessment Programme AMAP 2021: Mercury in the Arctic. Oslo, Norway. In press.
45. Abass K., Calsen A., Rautio A., Approches to desribe risks and future needs, In Arctic Monitoring and Assessment Programme AMAP 2015, Oslo, Norway, ISBN: 978-82-7971-093-6
46. Abass K., Abd-El-Razik M., Abouelghar G., Fate and disposition of chlorpyrofos in human, In Chlorpyrifos: Technical properties, uses and effect on human health and the environment. Nova Science Publishers, New York, USA. ISBN: 978-1-63482-111-7
47. Abass K., Turpeinen M., Rautio A., Hakkola J., Pelkonen O. (2012). Metabolism of pesticides by human cytochrome P450 enzymes in vitro – survey. In: Insecticides - Advances in Integrated Pest Management– Farzana Perveen (Ed.) ISBN 979-953-307-667-5, pp. 165-194., Rijeka, Croatia
48. Abass K., Reponen P, Turpeinen M, Sampo M, Pelkonen O. (2010). Do cytochrome P450 enzymes contribute to the metabolism of xenobiotics in human? In: Fungicides (Carisse O., Eds), ISBN: 978-953-307-266-1, pp. 441-468. Rijeka, Croatia
49. Abass K., Reponen P, Pelkonen O. (2009) Metabolic and interaction properties of selected fungicides, In Fungicides: Chemistry, Environmental, Impact and Health Effects (P. De Costa and Bezerra, Eds.), pp. 25-62. Nova Science Publishers, New York, USA.

Doctoral dissertation

50. Khaled M. Abass: Metabolism and interactions of pesticides in human and animal in vitro hepatic models. University of Oulu, Acta Universitatis Ouluensis, D Medica 1071 (2010). ISBN 978-951-42-6299-9.

• Member of American college of Toxicology, USA, Full member
• Member of European Society of Toxicology in vitro (ESTIV)
• Member of Finnish Society of Toxicology (FST)
• Member of International Society for the study of Xenobiotics (ISSX)

• One Health - One Future, Fairbanks, USA. 2020
• Environmental mercury research in a post-Minamata Convention world - Canadian Chemistry Conference and Exhibition, Winnipeg, Canada. 2020
• AMAP-Human Health expert group meeting & Problems of health maintenance and sanitary-epidemiological wellbeing provision of Arctic populations, St. Petersburg, Russia, 2019
• One Arctic - One Health Conference, Oulu, Finland, 2019
• 5th European Conference on Permafrost Mont Blanc, France, 2018
• Climate change effects on the epidemiology of infectious diseases and the impact on Northern societies (CLINF) Stakeholders workshop, Abisko, Sweden 2018
• UArctic Congress, Oulu and Helsinki, Finland, 2018
• 17th International Congress of Circumpolar Health, ICCH17, Copenhagen, Denmark, 2018
• In vitro comparative metabolism studies in Regulatory Pesticide Risk Assessment" European Food Safety Authority, Parma, Italy. 2018
• Human Toxicology & Environmental Medicine Symposium; Centre for Arctic Health, Aarhus University Aarhus, Denmark, 2018
• 47th Arctic Monitoring and Assessment Programme, Human Health Assessment Group, Ivalo, Finland 2017
• Society of Toxicology 55th Annual meeting and ToxExpo New Orleans, USA, 2016
• American College of Toxicology 36th Annual Meeting, Nevada/USA, 2015

• Health risk assessment of reproductive toxicity and endocrine disruptors Karolinska Institute, Stockholm, Sweden, 2018
• Computational toxicology - methods and applications, Karolinska Institute, Stockholm, Sweden, 2018
• Juvenile Toxicity Studies, Defining, and Overcoming the Challenges, American College of Toxicology, USA, 2015
• Selection and Use of Non-Rodent Species for Nonclinical Safety Assessment—Benefits, Pitfalls, and Caveats, American College of Toxicology, USA, 2015
• Computer modeling of toxicokinetics and cellular signaling pathways Karolinska Institute, Stockholm, Sweden, 2013
• Health Risk Assessment – principles and applications, Karolinska Institute, Stockholm, Sweden, Karolinska Institute, Stockholm, Sweden, 2012
• Modelling the impact of global climate change on the environmental fate of organic substances, Stockholm University, Sweden, 2012

• 2016 and 2017 - Thailand International Development Cooperation Agency fellowship award
• 2016 - Society of Toxicology IUTOX/SOT Endowment Fund
• 2015 - American College of Toxicology Award
• 2009 - Orion Pharma research Foundation, Finland
• 2008, 2009 and 2010 - Foundation of Economic Association in the Oulu, Finland.
• 2008 - Oulu University Scholarship Foundation grant, Finland