Projects of OPEM

Biophotonics

• Adaptive metamaterials for smart standalone histopathology with polarized light (META-HILIGHT) (2022-2024) H2020 Attract
• High-speed fibre-based Brillouin analyzer for endoscopy (HiFi Brilliancy) (2022-2024) H2020 Marie Curie
• Cloud processing of hyperspectral skin images (HyperCloud) (2021-2022)
• Hyperspectral and fluorescence measurements for the detection of diabetes complications (2021-2022) EduFI
• Effect of nanomaterials on blood microrheology in in vitro conditions (2020-2023) Academy of Finland mobility
• Non-invasive dynamic neural control by laser-based technology (Neuropa) (2020-2022) EU H2020 FET Open
• Smart Optical Biopsy with Twisted Light (Biopsy Twist) (2019-2023) Academy of Finland
• Hyperspectral Stokes polarization imaging for detection of biotissues abnormalities (HyperStokes) (2018-2022) Academy of Finland

Biomedical Sensors and Measurement Systems

• Accurate, deep tissue functional spectroscopy for a wide field of biomedical research (2022-2025) Infotech Oulu, Spearhead project

• Treating dementia by blood brain barrier opening to increase glymphatic clearance - From mechanisms to therapeutic applications (2021-2022) Academy of Finland, The Finnish Brain Foundation
• Glymphometer, wearable brain monitoring (2021-2022) Business Finland
• Advanced sensing of water during brain tumor radiotherapy and in neuro-oncologic multimodal MRI (2018-2022) Academy of Finland

Industrial Measurements

• Sharpening the image of the interplay between cloud top dynamics and microphysics / Consortium: SHARPCLOUD (2022-2026) Academy of Finland
• "Pilven ominaisuuksien erityistarkka mittaaminen holografiamikroskoopilla" (PERHO) (2022-2024) Jane and Aatos Erkko Foundation
• Time- and wavelength-resolved Raman and fluorescence confocal microscope based on integrated single-photon sensor (2022) University of Oulu & City of Oulu / PoC
• Digileap of oral health - towards virtual reception (2021-2022) ERDF
• Application of machine learning for risk assessment and a preliminary treatment path recommendation for dental diseases (-) DigiHealth NRI
• Ice Proof Arctic (IPA) (2019-2022) Interreg Nord

Printed Intelligence

• All-printed+ solid-state batteries for various applications (2022) University of Oulu & City of Oulu / PoC

• Energy- and cost-efficient production of solar energy under arctic environmental conditions (2021-2024) Kvantum Institute, Focus area spearhead project

• Printed Intelligence – enabler for safety in food chain (PrintoFood) (2021-2022) ERDF
• Printed Applications in Solid-State Batteries - PASS (2020-2022) ERDF
• Sustainable Solid-State Lithium-ion Batteries (SolBat) (2020-2022) Interreg Nord
• Printed intelligence infrastructure (PII) ( 2019-2022) Academy of Finland

Biophotonics

• Twisted light for digital tissue diagnosis (TWILIGHT) (2018-2021)
• Flexible dynamic light scattering blood perfusion matrix sensor (FeatureSens) (2018-2021)
• Investigation of structured light propagation in complex random media, including bio-tissues (2017-2021)
• Optical tweezers as a non-invasive tool for revealing biophysical peculiarities of cells interaction in presence of nanomedical compounds (2017-2021)
• Investigation of spectral characteristics and optical properties of water-based biological samples in terahertz frequency band for diseases diagnostics (2017-2020)
• Multimodal optical methods for early diagnostics of diabetic foot ulcers (multiDiagnostics) (2015-2019)
• Study of red blood cell aggregation properties influenced by nanoparticles with optical tweezers and microscopy methods (2018-2019)
• Applications of laser speckle contrast imaging (LSCI) for monitoring blood flow and perfusion in human skin in vivo with a hyperspectral camera (2018-2019)
• Development of multi-wavelength imaging and data processing methods for ulcers diagnostics (2018-2019)
• Anthropomorphic Optical Phantom (2018-2019)
• Ultra-sensitive opto-electrochemical detection of liquid explosives fabrication (2017-2020)
• Surface plasmons at work: Visible and infrared light enhanced catalysis and gas sensing, in collaboration with Microelctronics and Environmental & Chemical Engineering, Univ. Oulu (SuPlaCat) (2014-2018)
• Effects of nanoparticles on red blood cell aggregation and deformability studied with optical tweezers (2017-2018)
• Laser speckle imaging of biotissue perfusion with a hyperspectral camera (2017-2018)
• Applications of nanocapsules in the medicine and phase visualizations of the cells with use off-axis digital holographic microscope with quasi-monochromatic partially spatially coherent illumination in transmission (2017-2018)
• Laser speckle imaging of biotissue perfusion with a hyperspectral camera (2016-2017)
• Investigation of structured light propagation in complex random media including bio-tissues (2016-2017)
• Flow characterization in microvessels with complex geometry using Doppler optical coherence tomography (2016-2017)
• Applications of nanocapsules in the medicine and phase visualizations of the cells with use off-axis digital holographic microscope with quasimonochromatic partially spatially coherent illumination in transmission (2016-2017)
• Hyperspectral imaging of skin chromophores and blood oxygenation (2016-2017)
• New measurement technique for quantitative measurement of reversible red blood cells aggregation aimed at clinical application (2016-2017)
• Experimental studies of optical properties of biological tissue at heating and imaging with upconversion nanoparticles (2015-2016)
• Towards the digital optical biopsy: Noninvasive diagnostics of biotissues with circularly polarized light (2015)
• Time-gated Raman spectroscopy as a novel modality for the assessment of skin carotenoid status and material characterization, collaboration with Electronics, Univ. Oulu (2015)
• Fluorescence and elastic scattering tissue polarimetry for advanced non-invasive tissue diagnosis (2015)
• Upconversion nanoparticles as a novel platform for cancer diagnostics (2015)
• Plasmon-resonant nanostructures for optical imaging and therapy (2014-2016)
• Optical clearing of biological tissues to facilitate nanoparticle-mediated deep-tissue optical imaging (2014-2015)
• Development of ultralow forces measurement techniques with laser tweezers and implications to the red blood cells interaction mechanism (2014-2015)
• Nanocomposites containing drug-loaded hollow mesoporous silica and gold nanoparticles: multifunctional capability of fluorescence diagnostic, photothermolysis and drug delivery (2012-2013)
• Evaluation and diagnostics of biotissues by noninvasive high-resolving methods of optical coherence tomography and 3D microscopy, in collaboration with ITMO University, Russia (2011-2013)
• Diffraction phase microscopy with coherent and partially coherent light (2015-2016)
• Biophotonics technologies for novel diagnostic and therapeutic applications - FiDiPro  (2011-2014)
• Photo-acoustic imaging of bone surface vibrations for rapid and accurate assessment of osteoporosis (PAQUS) (2010-2013)
• Optical techniques for investigating light scattering in biological materials (2009-2011)
• Multimodal Estimation of Brain Oscillations (MEBO)  (2008-2011)
• Ultrashort laser pulse interactions with biological structures at tissue, cellular, and molecular levels  (2008-2010)
• Surgical, Interactive Robot developed into magnetic resonance tomography (SIRO)  (2005-2007)

Biomedical Sensors and Measurement Systems

To be added...

Industrial Measurements

• Single-photon detector array for simultaneous label-free Raman and fluorescence lifetime spectroscopy, Consortium: Digi-photon-Det (2018-2021) Academy of Finland

• DENTSAVER: 2018-2019
• CRYSTAL: Silmänpohjakuvien analysointi (Challenge Finland, Tekes, 2016)
• ALKYON: Havaintoteknologia liikenteen, ympäristön ja energiatuotannon turvallisuusinnovaatioihin (Challenge Finland, Tekes, 2016)
• CARDS: Computer aided radiology diagnostics system  (TUTL, Tekes, 2015-2016)
• ICEMET: Icing condition management in wind (TUTLI, Tekes, 2016-2017)
• ÄLYVESI: Älykkäät vesiprosessit ja monitorointi (Tekes, 2016)
• SIMP: System Integrated Metal Processes (Fimecc SHOK)
• PREMIUM: Prosessinesteen metallipitoisuuden älyk...  (TUTL, Tekes)
• REALMET: Reaaliaikainen integroitu...  (Tekes)

Printed Intelligence

• Novel digitally fabricated materials for electronics, optics and medical applications (NOVIDAM) (2018-2021) ERDF
• Taming the Coffee Ring Effect, Academy of Finland, 2016-2019
• Hilla WP2 Flex-in-Glass, 2017-2018
• Metrology for Highly Parallel Manufacturing - EMPIR Projects, (EURONET, EU)
• HILLA DIAMOND, 2015-2016
• PrintoCent Pilot Factory (EAKR)
• PrintoCent Business Development 2015-2017
• Solar energy harvesting sticker (The Centre for Environment and Energy (CEE))
• Fimecc Hybrids (Tekes SHOK)
• Syncronized Thermography for LED
• Fast optical layer thickness measurement
• Fast Optical Thickness measurement
• PAMS: Printed activity and motion sensors (Tekes)
• Start&run: Printocent Start&run (EAKR)
• PAALUTUS 2 (Tekes)
• PAALUTUS (Tekes)
• EMO (EAKR)
• AUTOSYS: Autonomous R2R systems (Tekes)
• The Center for printing of nano-to-mega photonics, electronics, and bioinformatics - FiDiPro (Academy of Finland) [Description]
• OLET: Novel approaches to printed organic light emitting field effect transistors (Academy of Finland) [Description]
• PrindemoPOC: PrintoCent proof-of-concepts and demonstrators  (Tekes)
• OPTOOLS: Optical tools for quality controlling of printed Intelligence (investment project) (EAKR)
• IDOLED: Commercialization of flexible OLEDs for RFID smart card applications (Tekes)
• POLYNET: Network of excellence for exploitation of organic and large are electronics (EU)
• PESEP: Printable electronics based sensor platform (Tekes)
• PAINE: Research environment for printed electronics and biomaterials (EAKR)
• PAINE2: Research environment for printed electronics and biomaterials -Phase 2 (EAKR)
• SEGASE: New selective gas sensors based on printed semiconductor nanoparticles (Tekes)
• PRINDEMO: Demonstrators of printed electronics (Tekes EAKR)
• PEOMIT: Printable electronics and optical measurement techniques (Tekes)
• Nano-to-Mega