Causative mechanisms & integrative models linking early-life-stress to psycho-cardio-metabolic multi-morbidity (EarlyCause)


EU H2020 funded project 2020-2023. University of Oulu PI Professor Sylvain Sebert.



Project information

Project duration


Funded by

Horizon 2020 - Research & Innovation Action (RIA)

Funding amount

508 000 EUR

Project coordinator

Other university or unit

Contact information

Project leader

Contact person

Project description

Stress experienced in the early stages of life – from pregnancy to adolescence – is common and pervasive, affecting up to 75% of pregnant women (and the unborn baby) and nearly 50% of children, with long term consequences for development and health. The EarlyCause project will study the hypothesis that early life stress (ELS), a well-established risk factor for depressive, cardiovascular and metabolic disorders individually, is a cause of multi-morbidity in these disorders.

Coordinator: Universitat De Barcelona


  1. European Molecular Biology Laboratory
  2. Erasmus Universitair Medisch Centrum Rotterdam
  3. Universitat Zurich
  4. King's College London
  5. Agencia Estatal Consejo Superior de Investigaciones Cientificas
  6. Centre Europeen de Recherche en Biologie et Medecine
  7. Oulun yliopisto
  8. Provincia Lombardo Veneta - Ordineospedaliero di San Giovanni di Dio- Fatebenefratelli
  9. University of Bath
  10. Stichting Vumc
  11. Empirica Gesellschaft fur Kommunikations und Technologieforschung Mbh
  12. Combinostics Oy
  13. Universidad Pompeu Fabra

Official EarlyCause project website