Alcohol use, alcohol polygenic score and cognition in schizophrenia, schizoaffective disorder, bipolar disorder, and a middle-aged birth cohort.
Thesis event information
Date and time of the thesis defence
Place of the thesis defence
Auditorium 1, PT1 108, Research Unit of Clinical Neuroscience, Peltolantie 17, Building PT1, FIN-90220, Oulu, Finland.
Topic of the dissertation
Alcohol use, alcohol polygenic score and cognition in schizophrenia, schizoaffective disorder, bipolar disorder, and a middle-aged birth cohort.
Doctoral candidate
PhD student Atiqul Mazumder
Faculty and unit
University of Oulu Graduate School, Faculty of Medicine, Research Unit of Clinical Neuroscience
Subject of study
Psychiatry
Opponent
Professor Soili Lehto, University of Oslo, Norway
Custos
Professor Juha Veijola, University of Oulu
Alcohol use and cognitive functions in psychotic patients.
Self-reported alcohol use was not associated with poorer cognition in schizophrenia and bipolar disorder patients. On the other hand, alcohol use disorder was associated with poor cognition in patients with psychotic disorder. Alcohol polygenic score was not associated with cognition in schizophrenia or bipolar disorder patients.
The aim of the study was to investigate the association between alcohol use, alcohol use disorder, and polygenic risk of alcohol use and cognition in patients with psychotic disorder. The psychiatric patients included 10,417 participants who had a clinical diagnosis of schizophrenia or bipolar disorder.
Our results suggest that moderate alcohol use might not be harmful for cognition in patients with psychotic disorder. However, the findings should be interpreted cautiously, and no clinical conclusions can be drawn until the results of this study are replicated in other studies.
The aim of the study was to investigate the association between alcohol use, alcohol use disorder, and polygenic risk of alcohol use and cognition in patients with psychotic disorder. The psychiatric patients included 10,417 participants who had a clinical diagnosis of schizophrenia or bipolar disorder.
Our results suggest that moderate alcohol use might not be harmful for cognition in patients with psychotic disorder. However, the findings should be interpreted cautiously, and no clinical conclusions can be drawn until the results of this study are replicated in other studies.
Last updated: 23.1.2024