OASIS - Organ-on-chip platform for in situ detection of osteoarthritis biomarkers
OASIS
![](https://media-cdn.oulu.fi/styles/main_image/s3/images/Composite3dstatic-tilescan_0.jpg?itok=SMP0w3Kb)
Project information
Project duration
-
Funded by
Other Finnish
Project funder
Funding amount
213 958 EUR
Project coordinator
University of Oulu
Contact information
Contact person
Researchers
Project description
OASIS aims to develop a biomimetic in vitro model of osteoarthritis (OA) building-on the preexisting and well-demonstrated bone marrow in vitro model from Finnadvance. These microfluidic models, appropriately termed as organ-on-chip (OoC), will allow for highly parallelized and replicable OA pathology simulation on standardized chip platform. Our approach also solves the second initiative of pre-emptive sensing by employing an integrated modular biochemical sensing platform based on carbon nanotube sensing elements coupled to electrochemical detection. This project advances preemptive predictive care and sensing methodologies, over the current postdiagnosis cures. Early detection is key for reduced burden from OA and OA-related health and economic losses globally.