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Research

We are a multi-disciplinary neuroimaging research group at the University of Oulu and Oulu University Hospital.

The research is focused on developing new methods for analysis of functional neuroimaging data within multiple scales - both time and space. We have latest technology of measuring slow single cell potentials from hippocampal slices and sympathetic nervous system fluctuations in humans. We have created a novel multimodal scanning environment, which combines latest development within functional magnetic resonance imaging called magnetic resonance encephalography (MREG) combined with MRI compatible electroencephalography (EEG), near-infrared spectroscopy (NIRS) and continuous non-invasive blood pressure (NIBP) measurements. Our aim is to form a picture of neuronal activity from single cells to neuronal networks based on slow neuronal fluctuations.

We collaborate with several clinical research groups which focus on psychiatric and neurologic disorders like schizophrenia, dementia, epilepsy and autism. In 2014 we have initiated CNS lymphoma research focusing on BBBD multimodal monitoring. We are also well established research site within the international neuroimaging realm.

In 2015 we developed a method to detect short-term activity avalanches in human with ultrafast MREG.

We were able to identify glymphatic pulsation in human brain in 12/2015 with ultrafast MREG. We also detected two new mechanisms of glymphatic pulsation (Kiviniemi et al., JCBFM 2015). A quick report on the importance was summerized in New Scientist under the title How waste pulses through your brain.

OFNI-group is associated with Medical Research Center (MRC), Oulu BioImaging, University of Oulu Graduate School (UniOGS) and are a part of the MIPT (Medical Imaging, Physics and Technology).

Vesa Kiviniemi: Functional segmentation of the brain cortex based on resting state signal sources. Advanceds in resting-state fMRI symposium 2009, Stanford University.

Last updated: 14.7.2017