Mechanisms and applications of disulfide bond formation

Lloyd Ruddock, Ph.D.

Project leader
Prof. Lloyd Ruddock, Ph.D.

Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine

Mailing address
P.O.Box 3000, FIN-90014 University of Oulu, Finland

Street address
University of Oulu, Aapistie 7A, 90220 Oulu, Finland

Tel: +358-(0)294 481683,
e-mail: lloyd.ruddock (at)

Focus area spearhead project web page

About the project

The research undertaken in this project aims to develop efficient systems for the production of disulfide bond containing proteins in the cytoplasm of E.coli and to use these for examining structure-function relationships of proteins. Our system is already approaching levels of CHO for the production of aglycosylated full length antibodies.

Project details

  1. Background and Significance
  2. Recent Progress
  3. Future Goals
  4. Publications 2017-
  5. Patents 2017
  6. Research Group Members

Last updated: 15.10.2018