PEDEGO Research Unit, and Biocenter Oulu, University of Oulu; Medical Research Center, Oulu University Hospital, Oulu, Finland
P.O.Box 5000, FIN-90014 University of Oulu, Finland
Aapistie 5A, Biocenter Oulu, 3rd floor, 90220 Oulu, Finland
Focus area spearhead project web page:
About the project
Our research aim is to clarify the functional mechanisms caused by novel genetic factors in human disease pathogenesis that could be potentially treatable by drugs in future. Recently, exome sequencing, functional and bioinformatics studies carried out within a collaboration network have led us to identify novel factors with previously unknown functions involved in cell energy metabolism and cellular signalling pathways. In this project, pathomechanisms are studied in detail by using mice, zebrafish, fruit flies and patient-derived cell lines. Our project will bring valuable information about factors enriched in Northern Finland that are related to neurodegenerative diseases.
Last updated: 15.10.2018