The Northern Finland Birth Cohorts (NFBC1966 with expected date of birth in 1966; NFBC1986 with expected date of birth between July 1985 and June 1986) offer an unparalleled opportunity to study multiple determinants of disorders, diseases and their intermediate stages.
Taking advantage of forthcoming and existing data collections and collaborations we will:
- Further uncover genetic, epigenetic and early predictors of the disease-related phenotypes of paramount importance for public health using genetic-multi-omics systems biology, bioinformatics and experimental research approaches to gain further insights into disease mechanisms and pathogenesis over the life-course.
- Investigate the interplay of environmental and genetic factors in the aetiology of disorders and their intermediate phenotypes in collaboration with other comparable studies.
Provide an enhanced evidence base to inform the development of preventive strategies and involvement of potential commercial organisations to reduce the public health burden of diseases.
We have well established collaboration with world’s leading teams/researchers in the field.
NFBCs are part of several consortia and programs, such as the Early Growth and Genetics Study Consortium, the Early Genetics and Lifecourse Epidemiology Consortium, Genetic Investigation of Anthropometric Traits, the EU funded European Network of Genomic and Genetic Epidemiology program (finished in 2012), STAMPEED program (finished in 2009, but work is ongoing), SUNLIGHT (Study of Underlying Genetic Determinants of VitD and Highly Related Traits), and PrevMetSyn (Improved Methods of Lifestyle Modification for Patients at High Risk for Metabolic Syndrome, Academy of Finland).
Northern Finland Birth Cohorts are part of Identifying Trajectories for Healthy Aging -consortium (Academy of Finland funding for NFBC and Biobanks) and part of two other Academy of Finland funded consortia FINMIC (aims to identify the relationship between early childhood microbiome and allergies, asthma, and chronic low-grade inflammation combining data from eight Finnish cohorts) and PSYCOHORTS (aim to harmonize data from seven Finnish birth cohorts).
We are partners in Biocenter Oulu, at the University of Oulu and in two large scale epigenetic projects funded from 2012 by the EU (EpiMigrant, and EurHealthAging). At University of Oulu we are coordinator of DynaHealth project (funded by the EU 2015) and partner of LifeCycle project (funded by EU 2017).